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TDP-43とRNAグアニン四重鎖の相互作用及びその破綻の研究

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TDP-43とRNAグアニン四重鎖の相互作用及びその破綻の研究

Material type
文書・図像類
Author
石黒, 亮ほか
Publisher
-
Publication date
2021-05-20
Material Format
Digital
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研究分野:分子生物学

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研究成果の概要 (和文) : TDP-43は筋萎縮性側索硬化症(ALS)や前頭側頭葉変性症(FTLD)など神経変性疾患の神経細胞内で凝集体の形成やアミノ酸変異が同定されているRNA結合タンパク質である。研究代表者はTDP-43がグアニン四重鎖結合タンパク質であることを発見。10種のALS変異タンパク...

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  • HOSEI UNIVERSITY REPOSITORY

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Digital

Material Type
文書・図像類
Author/Editor
石黒, 亮
ISHIGURO, Akira
Publication Date
2021-05-20
Publication Date (W3CDTF)
2021-05-20
Alternative Title
Study of interaction between TDP-43 and RNA guanine quadruplex and its disruption
Periodical title
科学研究費助成事業 研究成果報告書
Pages
1-6
Text Language Code
jpn