ヒト肝細胞キメラマウスを用いたNS5A阻害薬耐性変異型HCVとDAA療法の関連性の研究 1) NS5A阻害薬治療不成功例におけるNS5A耐性関連変異およびヒト肝細胞キメラマウスを用いたNS5A-P32欠失変異を持つC型肝炎ウイルスに対する有効な治療法の検討 2) NS5A阻害薬治療不成功例におけるダクラタスビル/アスナプレビル/ベクラブビル治療の問題点について
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- Material Type
- 博士論文
- Author/Editor
- 寺岡, 雄吏
- Author Heading
- Alternative Title
- Association between resistance-associated NS5A variants of hepatitis C virus and efficacy of direct-acting antivirals in human hepatocyte transplanted mice 1) Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice 2) Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure
- Degree grantor/type
- 広島大学
- Date Granted
- 2019-09-20
- Dissertation Number
- 甲第7998号
- Degree Type
- 博士(医学)Doctor of Philosophy in Medical Science
- Text Language Code
- eng