Short-term drug-drug interaction between sildenafil and bosentan under long-term use in patients with pulmonary arterial hypertension

• Material Type: 博士論文
• Title: Short-term drug-drug interaction between sildenafil and bosentan under long-term use in patients with pulmonary arterial hypertension
• Author/Editor: Miyakawa, Sachiko
• Author Heading: Miyakawa, Sachiko
• Publication, Distribution, etc.: Scientific Research Publishing
• Publication Date: 2013
• Publication Date (W3CDTF): 2013
• Alternative Title: 肺動脈性肺高血圧症患者における長期的なシルデナフィルとボセンタン使用下での両薬物の短期的薬物間相互作用
• Periodical title: Pharmacology & Pharmacy
• No. or year of volume/issue: 4 7
• Volume: 4
• Issue: 7
• Pages: 542-548
• ISSN (Periodical Title): PISSN : 2157-9423; EISSN : 2157-9431
• Degree grantor/type: 浜松医科大学
• Date Granted: 2014-03-17
• Dissertation Number: 甲第672号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Drug-Drug Interaction; Pulmonary Arterial Hypertension; Sildenafil; Bosentan; Pharmacokinetics
• Target Audience: 一般
• Note (General): doctoral; 医学系研究科
• Format (IMT): application/pdf
• Source: 論文本文 （fulltext）; https://hama-med.repo.nii.ac.jp/record/2651/files/DT_672ronbun.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.4236/pp.2013.47078
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 浜松医科大学 : 浜松医科大学学術機関リポジトリ

• Summary, etc.: Sildenafil and bosentan are often co-administered for pulmonary arterial hypertension (PAH) treatment. The plasma concentration of sildenafil can be d...