Dexmedetomidine suppresses serum syndecan-1 elevation and improves survival in a rat hemorrhagic shock model

• Material Type: 博士論文
• Title: Dexmedetomidine suppresses serum syndecan-1 elevation and improves survival in a rat hemorrhagic shock model
• Author/Editor: 小林, 充
• Author Heading: 小林, 充
• Publication, Distribution, etc.: 日本実験動物学会
• Publication Date: 2022-07
• Publication Date (W3CDTF): 2022-07
• Alternative Title: デクスメデトミジンはラット出血性ショックモデルにおいて血清シンデカン-1の上昇を抑制し生存率を改善する
• Periodical title: Experimental Animals
• No. or year of volume/issue: 71 3
• Volume: 71
• Issue: 3
• Pages: 281-287
• ISSN (Periodical Title): PISSN : 1341-1357; EISSN : 1881-7122
• Degree grantor/type: 浜松医科大学
• Date Granted: 2022-03-14
• Dissertation Number: 甲第901号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: cholinergic pathway; dexmedetomidine; endothelial glycocalyx; hemorrhagic shock
• Target Audience: 一般
• Note (General): J-STAGEにて、最終版の公開あり。; The final version of this article is available on J-STAGE.; doctoral; 医学系研究科
• Format (IMT): application/pdf
• Source: 論文本文 （fulltext）; https://hama-med.repo.nii.ac.jp/record/4095/files/DT_901ronbun.pdf
• Access Restrictions: インターネット公開
• Rights (production): Copyright 2022 Japanese Association for Laboratory Animal Science; This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <http://creativecommons.org/licenses/by-nc-nd/4.0/>.
• Related Material (DOI): 10.1538/expanim.21-0186
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 浜松医科大学 : 浜松医科大学学術機関リポジトリ

• Summary, etc.: Hemorrhagic shock causes vascular endothelial glycocalyx (EGCX) damage and systemic inflammation. Dexmedetomidine (DEX) has anti-inflammatory and EGCX...