UBL3 interacts with alpha-synuclein in cells and the interaction is downregulated by the EGFR pathway inhibitor osimertinib

• Material Type: 博士論文
• Title: UBL3 interacts with alpha-synuclein in cells and the interaction is downregulated by the EGFR pathway inhibitor osimertinib
• Author/Editor: Chen, Bin
• Author Heading: Chen, Bin
• Publication, Distribution, etc.: MDPI
• Publication Date: 2023-06-10
• Publication Date (W3CDTF): 2023-06-10
• Alternative Title: UBL3は細胞内でα-シヌクレインと相互作用し、その相互作用はEGFR経路阻害剤オシメルチニブによってダウンレギュレーションされる
• Periodical title: Biomedicines
• No. or year of volume/issue: 11 6
• Volume: 11
• Issue: 6
• Pages: 1685-
• ISSN (Periodical Title): EISSN : 2227-9059
• Degree grantor/type: 浜松医科大学
• Date Granted: 2023-09-22
• Dissertation Number: 甲第952号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: UBL3; α-synuclein; interaction; drug screen; EGFR pathway inhibitor; osimertinib; downregulate; α-synucleinopathies
• Target Audience: 一般
• Note (General): doctoral; 医学系研究科
• Format (IMT): application/pdf
• Source: 論文本文 （fulltext）; https://hama-med.repo.nii.ac.jp/record/2000200/files/DT_952ronbun.pdf
• Access Restrictions: インターネット公開
• Rights (production): (C) 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
• Related Material (DOI): 10.3390/biomedicines11061685
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 浜松医科大学 : 浜松医科大学学術機関リポジトリ

• Summary, etc.: Ubiquitin-like 3 (UBL3) acts as a post-translational modification (PTM) factor and regulates protein sorting into small extracellular vesicles (sEVs)....