ダイナミックリアクションセル^TM-誘導結合プラズマ質量分析法による糖尿病患者尿及び血清中の微量元素分析

Material type: 文書・図像類

Author: 上田, 寿ほか

Publisher: 愛知工業大学

Publication date: 2009-09-24

Material Format: Digital

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Note (General)：: To assess whether differences in concentrations of trace elements between diabetics and controls can be regarded as significant，V，Cr，Ni，Cu，As and Se i...

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Material Type: 文書・図像類
Title: ダイナミックリアクションセル^TM-誘導結合プラズマ質量分析法による糖尿病患者尿及び血清中の微量元素分析
Author/Editor: 上田, 寿
手嶋, 紀雄
酒井, 忠雄
加藤, 周司
Author Heading: 上田, 寿
手嶋, 紀雄
酒井, 忠雄
加藤, 周司
Publication, Distribution, etc.: 愛知工業大学
Publication Date: 2009-09-24
Publication Date (W3CDTF): 2009-09-24
Alternative Title: ダイナミック　リアクション　セル　TM　ユウドウ　ケツゴウ　プラズマ　シツリョウ　ブンセキ　ホウ　ニヨル　トウニョウビョウ　カンジャ　ニョウ　オヨビ　ケッセイチュウ　ノ　ビリョウ　ゲンソ　ブンセキ
Analysis of Trace Elements in Diabetic Human Urine and Serum by Dynamic Reaction Cell^TM Inductively Coupled Plasma Mass Spectrometry
Periodical title: 総合技術研究所研究報告=Bulletin of Research Institute for Industrial Technology.
No. or year of volume/issue: 11
Volume: 11
Pages: 37-44
ISSN (Periodical Title): ISSN : 1344-9672
Text Language Code: jpn
Target Audience: 一般
Note (General): To assess whether differences in concentrations of trace elements between diabetics and controls can be regarded as significant，V，Cr，Ni，Cu，As and Se in urinary and serum samples from diabetics and healthy volunteers were determined by dynamic reaction cell (DRC™) inductively coupled plasma mass spectrometry. To obtain lower background of each element, DRC™ conditions such as ammonia used as reaction cell gas and rejection parameter q (RPq) were optimized for the measurement. This method with optimum conditions was validated by the analysis of standard reference materials of urine and serum. The results were in good agreement with the certified values. Urine samples supplied from patients (n = 29) with diabetes and from healthy volunteers (n = 11) were analyzed by this method, and the results were assessed by Students t-test at significance level of 0.05. As a result, no statistical significance was observed for urinary V, Ni, As and Se (P > 0.05). However, the concentrations of urinary Cu and Cr in the diabetic group were higher than those in healthy group (P < 0.05). On the other hand the concentration of Cr in serum (n = 19) from patients with diabetes was lower than reference value of serum Cr in controls.
identifier:http://repository.aitech.ac.jp/dspace/handle/11133/1694
Access Restrictions: 限定公開
Periodical Title (NCID): AA11484797
https://ci.nii.ac.jp/ncid/AA11484797
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 愛知工業大学 : 愛知工業大学学術情報リポジトリ