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- Material Type
- 規格・テクニカルリポート類
- Author/Editor
- 渡部 陽子木名瀬 栄斎藤 公明
- Publication Date
- 2007-03
- Publication Date (W3CDTF)
- 2007
- Alternative Title
- Evaluation of energy deposition to the urinary bladder wall considering radiosensitive basal cells by beta-ray emitters
- Periodical title
- JAEA-Research 2007-011
- Target Audience
- 一般
- Note (General)
- 出版タイプ： NA本報告書は、放射線診断による吸収線量が他の臓器よりも高くなる傾向にある膀胱の線量評価について述べるものである。より適切な線量評価を行うために、膀胱の放射線感受性の高い細胞である基底細胞を考慮した膀胱簡易モデルを構築し、光子,電子に対する基底細胞や膀胱壁全体の比吸収割合(SAF)をモンテカルロシミュレーションにより評価した。また、評価したSAFを用いてベータ線放出核種36核種における単位放射能あたりの標的組織の平均吸収線量(S値)を求めた。その結果、より信頼性の高い膀胱の線量評価をより正確に行ううえで、標的組織として基底細胞の深さを決定することやベータ線スペクトルなどの放射線エネルギー情報を考慮することが極めて重要であることがわかった。The present report describes the dose evaluation of the urinary bladder since its absorbed dose from radiopharmaceuticals tends to be higher than other organs. For an accurate dose evaluation, a simple bladder model considering radiosensitive basal cells was used to calculate SAF (specific absorbed fractions) for the basal cells and the whole bladder wall from mono energetic photon and electron sources using Monte Carlo simulation. Furthermore, S values (the mean absorbed doses for the target organ per unit cumulated activity in the source organ) were evaluated for 36 beta-ray emitters. Consequently, considering basal cells and beta particle spectra in the evaluation of absorbed dose for the urinary bladder are very important for an accurate evaluation.
- Source
- /JAEA-Research-2007-011.pdf （fulltext）