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Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
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Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
- Material type
- 記事
- Author
- Yuji Shibaほか
- Publisher
- Springer Science and Business Media LLC
- Publication date
- 2016-10
- Material Format
- Digital
- Journal name
- Nature 538 7625
- Publication Page
- p.388-391
Detailed bibliographic record
Summary, etc.:
- Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-specific cardiomyocytes for cardiac repair, providing a maj...
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Digital
- Material Type
- 記事
- Author Heading
- Publication Date
- 2016-10
- Publication Date (W3CDTF)
- 2016-10
- Periodical title
- Nature
- No. or year of volume/issue
- 538 7625
- Volume
- 538
- Issue
- 7625
- Pages
- 388-391
- Publication date of volume/issue (W3CDTF)
- 2016-10
- ISSN (Periodical Title)
- 00280836http://id.crossref.org/issn/00280836
- Publication (Periodical Title)
- Springer Science and Business Media LLC
- Subject Heading
- Target Audience
- 一般
- Standard No. (Other)
- PMID : 28449453
- DOI
- 10.1038/nature19815
- Date Created (W3CDTF)
- 2016-10-07
- Access Restrictions
- インターネット公開
- Rights (production)
- http://www.springer.com/tdm
- Related Material (URI)
- Is Referenced By
- MHC matching improves engraftment of iPSC-derived neurons in non-human primates.Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted MyocardiumTherapeutic potential of clinical-grade human induced pluripotent stem cell-derived cardiac tissuesRecent progress of animal transplantation studies for treating articular cartilage damage using pluripotent stem cellsGeneration of monkey iPS cell-derived cartilage lacking MHC class I molecules on the cell surfaceNK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCsCardiac regeneration with pluripotent stem cell-derived cardiomyocytes and direct cardiac reprogrammingPurification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sortingβ-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart RateCharacterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell TherapyEnhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytesIn vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imagingGeneration of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human diseaseImpact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct modelAm80, a retinoic acid receptor agonist, activates the cardiomyocyte cell cycle and enhances engraftment in the heartIncreased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivoCell Therapy Trials in Congenital Heart DiseaseThe addition of human iPS cell-derived neural progenitors changes the contraction of human iPS cell-derived cardiac spheroidsToward the realization of cardiac regenerative medicine using pluripotent stem cellsIntramyocardial Transplantation of Human iPS Cell–Derived Cardiac Spheroids Improves Cardiac Function in Heart Failure AnimalsNeural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healingPower of mitochondrial drug delivery systems to produce innovative nanomedicinesLow computational-cost cell detection method for calcium imaging dataONO-1301 enhances post-transplantation survival of human induced pluripotent stem cell-derived cardiac tissue sheet by promoting angiogenesisEngineered Tissue for Cardiac Regeneration: Current Status and Future PerspectivesRegeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell–Derived Cardiac SpheroidsMature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallinIdentification of novel polymorphisms and two distinct haplotype structures in dog leukocyte antigen class I genes: DLA-88, DLA-12 and DLA-64Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytesSafe and Effective Cardiac Regenerative Therapy With Human-Induced Pluripotent Stem CellsNano-structural analysis of engrafted human induced pluripotent stem cell-derived cardiomyocytes in mouse hearts using a genetic-probe APEX2No Tumorigenicity of Allogeneic Induced Pluripotent Stem Cells in Major Histocompatibility Complex-matched Cynomolgus MacaquesInduced Pluripotent Stem Cells 10 Years LaterEvaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation modelScalable manufacturing of clinical‐grade differentiated cardiomyocytes derived from human‐induced pluripotent stem cells for regenerative therapyDevelopment of direct cardiac reprogramming for clinical applicationsCardiac Regeneration Using Pluripotent Stem Cells and Controlling Immune ResponsesDevelopment of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivoUnlocking the Pragmatic Potential of Regenerative Therapies in Heart Failure with Next-Generation TreatmentsThe Exciting Realities and Possibilities of iPS-Derived CardiomyocytesInduced pluripotent stem cell–derived hematopoietic stem and progenitor cells induce mixed chimerism and donor-specific allograft toleranceDirect Reprogramming, Epigenetics, and Cardiac RegenerationInduced Pluripotent Stem Cells and Their Use in Human Models of Disease and DevelopmentA Brief Review of Current Maturation Methods for Human Induced Pluripotent Stem Cells-Derived CardiomyocytesFast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areasHeart regeneration using pluripotent stem cellsTherapeutic efficacy of large aligned cardiac tissue derived from induced pluripotent stem cell in a porcine ischemic cardiomyopathy modelProgress of iPS cell-based transplantation therapy for retinal diseasesCompetency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primatesSeamless and non-destructive monitoring of extracellular microRNAs during cardiac differentiation from human pluripotent stem cellsEstablishment of the Removal Method of Undifferentiated Induced Pluripotent Stem Cells Coexisting With Chondrocytes Using R-17F AntibodyCardiac Regenerative Therapy Using Human Pluripotent Stem Cells for Heart Failure: A State-of-the-Art ReviewPluripotent stem cell-based cardiac regenerative therapy for heart failureDeveloping Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial InfarctionGABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoterSustained release of basic fibroblast growth factor using gelatin hydrogel improved left ventricular function through the alteration of collagen subtype in a rat chronic myocardial infarction modelProgress and Challenge of Cardiac Regeneration to Treat Heart FailureEfficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic FunctionsInduced Pluripotent Stem Cells for Regenerative Medicine: Quality Control Based on Evaluation of Lipid CompositionPluripotent Stem Cell-Derived Cardiomyocyte Transplantation for Heart Disease TreatmentStrategies for immune regulation in iPS cell-based cardiac regenerative medicineProduction of functional cardiomyocytes and cardiac tissue from human induced pluripotent stem cells for regenerative therapyThe Present State and Future Perspectives of Cardiac Regenerative Therapy Using Human Pluripotent Stem CellsCurrent status and future perspectives of HLA-edited induced pluripotent stem cellsA Method for Cardiac Differentiation, Purification, and Cardiac Spheroid Production of Human Induced Pluripotent Stem CellsManipulating Cardiomyocyte Plasticity for Heart RegenerationTemperature Dependence of the Beating Frequency of hiPSC-CMs Using a MEMS Force SensorIntracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regenerationCD8+ T cell-mediated rejection of allogenic human-induced pluripotent stem cell-derived cardiomyocyte sheets in human PBMC-transferred NOG MHC double knockout miceA nonhuman primate model of liver fibrosis towards cell therapy for liver cirrhosisIn Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem CellsEvaluation of alloreactive T cells based on the degree of MHC incompatibility using flow cytometric mixed lymphocyte reaction assay in dogsLong-Term Outcome and Rejection After Allogeneic Uterus Transplantation in Cynomolgus MacaquesThe Cynomolgus Macaque MHC Polymorphism in Experimental Medicine分化心筋細胞を用いた重症心不全における再生医療研究Function follows form—A review of cardiac cell therapyDevelopment of social systems neuroscience using macaquesTherapeutic Potential of Pluripotent Stem Cells for Cardiac Repair after Myocardial InfarctionPluripotent Stem Cells for Cardiac Regeneration ― Current Status, Challenges, and Future Perspectives ―Direct Conversion of Cell Fate and Induced Endothelial CellsRecent Progress Using Pluripotent Stem Cells for Cardiac Regenerative TherapyHeart Regeneration for Clinical ApplicationHCN4-Overexpressing Mouse Embryonic Stem Cell-Derived Cardiomyocytes Generate a New Rapid Rhythm in Rats with BradycardiaNovel Players and a Target of Stem Cell Therapy for the Heart4)心臓再生医療の最前線Cell Therapy Strategies With No Safety Concerns and Demonstrated Benefits Warrant Study ― Reply ―
- References
- Genetically Encoded Green Fluorescent Ca2+ Indicators with Improved Detectability for Neuronal Ca2+ SignalsCardiomyocytes derived from MHC-homozygous induced pluripotent stem cells exhibit reduced allogeneic imunogenicity in MHC-matched non-human primatesAn Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood CellsHuman ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured heartsDiscovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencingA Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free ConditionsDistinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived CardiomyocytesTransplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction modelIPD—the Immuno Polymorphism DatabaseElectrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct ModelStudy of MHC class II region polymorphism in the Filipino cynomolgus macaque populationA simple method to optimize peripheral blood mononuclear cell preparation from cynomolgus monkeys and improve mixed lymphocyte reactionsExtracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem CellsInduced Pluripotent Stem Cells for Post–Myocardial Infarction RepairCardiac Applications for Human Pluripotent Stem CellsDendritic Cell Type Determines the Mechanism of Bystander Suppression by Adaptive T Regulatory Cells Specific for the Minor Antigen HA-1Heart regenerationFormation of Human Myocardium in the Rat Heart from Human Embryonic Stem CellsHuman embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate heartsDevelopment of Histocompatible Primate‐Induced Pluripotent Stem Cells for Neural TransplantationCardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heartsDifferential function of major histocompatibility complex antigens in T-lymphocyte activationCritical Role of Regulatory T Cells in Th17-Mediated Minor Antigen-Disparate RejectionThe major histocompatibility complex: a model for understanding graft-versus-host diseaseImpact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft
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- 国立情報学研究所 : CiNii Research
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