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多彩表現型血栓症を示すVWF特異的切断酵素の活性低下の病態解析

多彩表現型血栓症を示すVWF特異的切断酵素の活性低下の病態解析
Paper図書
藤村吉博, 奈良県立医科大学 [著][藤村吉博]2003-2005<Y151-H15591017>
National Diet Library
  • Subject HeadingTTP / ADAMTS13 / VWF

スポーツ活動時における血栓形成の発生機序の解明

スポーツ活動時における血栓形成の発生機序の解明
Paper図書
石指宏通, 奈良県立医科大学 [著][石指宏通]2005-2006<Y151-H17500439>
National Diet Library
  • Subject Headingスポーツ / VWF / ADAMTS13 / 循環血漿量 / 発汗

血栓性微小血管障害症での高度腎機能障害の成因としてのADAMTS-13解析

血栓性微小血管障害症での高度腎機能障害の成因としてのADAMTS-13解析
Paper図書
松本雅則, 奈良県立医科大学 [著][松本雅則]2004-2006<Y151-H16590796>
National Diet Library
  • Subject HeadingTMA / ADAMTS13 / VWF / 腎機能障害 / 膠原病 / TTP / H...

第8因子/VWF複合体の機能制御に基づく新しい抗血栓症戦略

第8因子/VWF複合体の機能制御に基づく新しい抗血栓症戦略
Paper図書
吉岡章, 奈良県立医科大学 [著][吉岡章]2005-2007<Y151-H17390304>
National Diet Library
  • Subject Heading第VIII因子 / VWF / 生理的血流 / 血栓症 / フローチャンバー / ADAMTS13

ずり応力により調節される血小板凝集と血栓形成過程の生体内リアルタイム解析

ずり応力により調節される血小板凝集と血栓形成過程の生体内リアルタイム解析
Paper図書
浦野哲盟, 浜松医科大学 [著][浦野哲盟]2006-2007<Y151-H18590204>
National Diet Library
  • Subject Heading血栓形成 / 生体内顕微鏡 / von Willebrand因子 / ADAMTS13 / 血栓性血小板減少性紫斑病 / 血小板 / 血管内皮細胞

ADAMTS13の解析と重症肝疾患における微小循環障害の発生機序の解明

ADAMTS13の解析と重症肝疾患における微小循環障害の発生機序の解明
Paper図書
植村正人, 奈良県立医科大学 [著][植村正人]2005-2007<Y151-H17590670>
National Diet Library
  • Subject HeadingADAMTS13 / 微小循環障害 / 肝星細胞 / 多臓器不全 / 肝硬変...

新生児の血栓症の病因・病態の解明と治療法の開発

新生児の血栓症の病因・病態の解明と治療法の開発
Paper図書
高橋幸博, 奈良県立医科大学 [著][高橋幸博]2005-2006<Y151-H17591147>
National Diet Library
  • Subject Heading新生児 / 血栓症 / VWF-CP / ADAMTS13 / TAFI / 血栓溶解療法 / 抗血栓薬 / 新生児用...

血栓性血小板減少性紫斑病の原因遺伝子ADAMTS13の研究

血栓性血小板減少性紫斑病の原因遺伝子ADAMTS13の研究
Paper図書
宮田敏行, 国立循環器病センター研究所 [著][宮田敏行]2005-2007<Y151-H17390285>
National Diet Library
  • Subject Heading血小板 / フォンビルブランド因子 / 血小板減少症 / 血栓性血小板減少性紫斑病 / ADAMTS13 / 性差 / 一般住民 / 臨床検査法

フォンビルブランド因子切断酵素ADAMTS13の生理生化学的解析

フォンビルブランド因子切断酵素ADAMTS13の生理生化学的解析
Paper図書
小亀浩市, 国立循環器病センター研究所 [著][小亀浩市]2005-2006<Y151-H17570126>
National Diet Library
  • Subject Headingフォンビルブランド因子 / ADAMTS13 / プロテアーゼ / 酵素 / 血液 / 血小板 / 血栓...

Regulation of von Willebrand factor by ADAMTS13 ameliorates lipopolysaccharide-induced lung injury in mice

Regulation of von Willebrand factor by ADAMTS13 ameliorates lipopolysaccharide-induced lung injury in mice
Digital博士論文障害者向け資料あり
Onodera, Yu, Mitani, Seiji, Hosoda, Chihiro, Takabayashi, Yoko, Sakata, Asuka, Kawasaki, Ryohei, Mori, Ryota, Ohshima, Chiaki, Nishio, Kenji, Sugimoto, Mitsuhiko, Soejima, Kenji, Mackman, Nigel, Shima, Midori, Tatsumi, KoheiSpringer2023-12
National Diet Library
  • Subject HeadingADAMTS13 Inflammation Lipopolysacchari...
  • Note (General)...-type, Vwf-/-, Adamts13-/-) and mice t......ombinant human ADAMTS13 compared with ...... increased VWF/ADAMTS13 ratio at the s......suggested that ADAMTS13 protein and other VWF-targeti...
  • Alternative TitleADAMTS13によるvon Willebrand因子の制御はマウスにおける...

Increased cleavage of von Willebrand factor by ADAMTS13 may contribute strongly to acquired von Willebrand syndrome development in patients with essential thrombocythemia

Increased cleavage of von Willebrand factor by ADAMTS13 may contribute strongly to acquired von Willebrand syndrome development in patients with essential thrombocythemia
Digital博士論文障害者向け資料あり
Kubo, Masayuki, Sakai, Kazuya, Hayakawa, Masaki, Kashiwagi, Hirokazu, Yagi, Hideo, Seki, Yoshinobu, Hasegawa, Atsushi, Tanaka, Haruyuki, Amano, Itsuto, Tomiyama, Yoshiaki, Matsumoto, MasanoriBlackwell Pub2022-07
National Diet Library
  • Subject HeadingADAMTS13 protein essential thrombocyth...
  • Note (General)...osed following ADAMTS13-mediatedcleava......, primarily by ADAMTS13, leadingto AVW......rand factor by ADAMTS13 may contribute strongly to ac...
  • Alternative TitleADAMTS13によるvon Willebrand因子の切断増加は、本態性血...

Ischaemia-reperfusion injury with Pringle's maneuver induces unusually large von Willebrand factor multimers after hepatectomy. 183

Ischaemia-reperfusion injury with Pringle's maneuver induces unusually large von Willebrand factor multimers after hepatectomy. 183
Digital博士論文障害者向け資料あり
Yoshikawa, Takahiro, Nomi, Takeo, Sakai, Kazuya, Hayakawa, Masaki, Hokuto, Daisuke, Matsuo, Yasuko, Sho, Masayuki, Matsumoto, MasanoriElsevier2019-11Thrombosis research
National Diet Library
  • Subject HeadingADAMTS13 Unusually large VWF multimers...
  • Note (General)... study. Plasma ADAMTS13 activity and V......esults: Plasma ADAMTS13 activity significantly decrea...

Complement activation associated with ADAMTS13 deficiency may contribute to the characteristic glomerular manifestations in Upshaw-Schulman syndrome. 170

Complement activation associated with ADAMTS13 deficiency may contribute to the characteristic glomerular manifestations in Upshaw-Schulman syndrome. 170
Digital博士論文障害者向け資料あり
Itami, Hiroe, Hara, Shigeo, Matsumoto, Masanori, Imamura, Shin, Kanai, Rie, Nishiyama, Kei, Ishimura, Masataka, Ohga, Shouichi, Yoshida, Makiko, Tanaka, Ryojiro, Ogawa, Yoshiyuki, Asada, Yujiro, Sekita-Hatakeyama, Yoko, Hatakeyama, Kinta, Ohbayashi, ChihoElsevier2018-10Thrombosis research
National Diet Library
  • Subject HeadingUpshaw-Schulman syndrome (USS) Renal biopsy ADAMTS13 C4d
  • Note (General)...tations in the ADAMTS13 gene, possibly......ity with local ADAMTS13 expression and......ical features, ADAMTS13 immunoreactivi......rage number of ADAMTS13-positive cells......with deficient ADAMTS13 expression and local compleme...
  • Alternative TitleUpshaw-Schulman症候群の糸球体障害には補体活性とADAMTS13欠損が関連している可能性がある

Plasma Level of von Willebrand Factor Propeptide at Diagnosis: A Marker of Subsequent Renal Dysfunction in Autoimmune Rheumatic Diseases. 26

Plasma Level of von Willebrand Factor Propeptide at Diagnosis: A Marker of Subsequent Renal Dysfunction in Autoimmune Rheumatic Diseases. 26
Digital博士論文障害者向け資料あり
Yada, Noritaka, Yoshimoto, Kiyomi, Kawashima, Hiromasa, Yoneima, Ryo, Nishimura, Nobushiro, Tai, Yoshiaki, Tsushima, Emiko, Miyamoto, Makiko, Ono, Shiro, Matsumoto, Masanori, Fujimoto, Takashi, Nishio, KenjiSage Publications2020-01-01Clinical and applied thrombosis/hemostasis
National Diet Library
  • Subject Heading...tor propeptide ADAMTS13 renal dysfunction SLE mutimer...
  • Note (General)...if, member 13 (ADAMTS13), and VWF mult......nt decrease of ADAMTS13 in patients with SARDs compar...

Involvement of the ADAMTS13-VWF axis in acute Kawasaki disease and effects of intravenous immunoglobulin. 179

Involvement of the ADAMTS13-VWF axis in acute Kawasaki disease and effects of intravenous immunoglobulin. 179
Digital博士論文障害者向け資料あり
Tsujii, Nobuyuki, Nogami, Keiji, Matsumoto, Masanori, Yoshizawa, Hiroyuki, Takase, Toshio, Tanaka, Ichiro, Sakai, Toshiyuki, Fukuda, Kazuyoshi, Hayakawa, Masaki, Sakai, Kazuya, Isonishi, Ayami, Matsuura, Kayoko, Fujimura, Yoshihiro, Shima, MidoriElsevier2019-07Thrombosis research
National Diet Library
  • Subject HeadingKawasaki disease ADAMTS13 von Willebrand factor Intrave...
  • Note (General)type:Thesis INTRODUCTION: ADAMTS13 modulates shea......VWF antigen to ADAMTS13 activity (VWF:Ag/ADAMTS13:AC) promotes P......VWF. A role of ADAMTS13 in Kawasaki di......involvement of ADAMTS13-VWF axis in th......DS: VWF:Ag and ADAMTS13:AC in 77 KD in......stribution and ADAMTS13-isoelectrofocu......p < 0.05), low ADAMTS13:AC (60.3 ± 23.......nd high VWF:Ag/ADAMTS13:AC ratio (3.70......VWF:Ag and low ADAMTS13:AC at Pre, and high VWF:Ag/ADAMTS13:AC ratio at 1 ......d free form of ADAMTS13 and increased ......plex form with ADAMTS13 and high-molec...... A high VWF:Ag/ADAMTS13:AC ratio was a...... A high VWF:Ag/ADAMTS13:AC ratio in acute-KD persiste...
  • Alternative Title...if, member 13 (ADAMTS13) の動態

ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: Implications for selection of plasma preparations for TTP treatment 53 12

ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: Implications for selection of plasma preparations for TTP treatment 53 12
Digital博士論文障害者向け資料あり
Hori, Yuji, Hayakawa, Masaki, Isonishi, Ayami, Soejima, Kenji, Matsumoto, Masanori, Fujimura, YoshihiroBlackwell Publishing2013-12Transfusion
National Diet Library
  • Subject HeadingIEF VWF-ADAMTS13 complex VWF ADAMTS13
  • Note (General)...d by deficient ADAMTS13 activity. Trea......ctor (VWF) and ADAMTS13, we used large......tion with anti-ADAMTS13 monoclonal ant......, and purified ADAMTS13 were analyzed ......hree groups of ADAMTS13 bands with pI ......ith congenital ADAMTS13 deficiency. Mi......enting the VWF-ADAMTS13 complex; these......P and purified ADAMTS13 down regulated...... almost normal ADAMTS13 activity, but ......ower levels of ADAMTS13 in complex with larger VWF mu...
  • Alternative Titleクリオ上清中の高分子VWFマルチマー非結合型ADAMTS13の存在:血栓性血小板減少性紫斑病の治療に、より効果的な血漿分...

Blood group antigen A on von Willebrand factor is more protective against ADAMTS13 cleavage than antigens B and H. 17 6

Blood group antigen A on von Willebrand factor is more protective against ADAMTS13 cleavage than antigens B and H. 17 6
Digital博士論文障害者向け資料あり
Hayakawa, Masaki, Kato, Seiji, Matsui, Taei, Sakai, Kazuya, Fujimura, Yoshihiro, Matsumoto, MasanoriJohn Wiley and Sons, Inc.2019-06Journal of thrombosis and haemostasis
National Diet Library
  • Subject HeadingABO(H) blood group ADAMTS13 multimer analysis shear stres...
  • Note (General)type:Thesis BACKGROUND: ADAMTS13 specifically c......lity of VWF to ADAMTS13. METHODS: Usin......of a VWF-DP by ADAMTS13 quantitatively......ective against ADAMTS13 cleavage than antigens B and ...
  • Alternative Titleフォンヴィレブランド因子に存在する血型A抗原は、ADAMTS13による切断に対してB・H抗原よりも抵抗性を示す

Von Willebrand Factor Aggravates Hepatic Ischemia-Reperfusion Injury by Promoting Neutrophil Recruitment in Mice. 118 4

Von Willebrand Factor Aggravates Hepatic Ischemia-Reperfusion Injury by Promoting Neutrophil Recruitment in Mice. 118 4
Digital博士論文障害者向け資料あり
Urisono, Yasuyuki, Sakata, Asuka, Matsui, Hideto, Kasuda, Shogo, Ono, Shiro, Yoshimoto, Kiyomi, Nishio, Kenji, Sho, Masayuki, Akiyama, Masashi, Miyata, Toshiyuki, Okuchi, Kazuo, Nishimura, Satoshi, Sugimoto, MitsuhikoThieme2018-04Thrombosis and haemostasis
National Diet Library
  • Subject Headingvon Willebrand factor ADAMTS13 hepatic ischaemia reperfusion...
  • Note (General)...nce of the VWF-ADAMTS13 (a disintegrin......an recombinant ADAMTS13 significantly ......tion of VWF by ADAMTS13 represents a promising therap...

Elevated plasma levels of soluble platelet glycoprotein VI (GPVI) in patients with thrombotic microangiopathy

Elevated plasma levels of soluble platelet glycoprotein VI (GPVI) in patients with thrombotic microangiopathy
Digital博士論文障害者向け資料あり
Yamashita, Yoshiki三重大学2014-12-10
National Diet Library
  • Subject HeadingTMA Platelet activation ADAMTS13 sGPVI
  • Note (General)...as decreased a ADAMTS13 level, activat......vels of sGPVI, ADAMTS13 activity, von ......rkedly reduced ADAMTS13 and those were significantly ...

Rapid Restoration of Thrombus Formation and High-Molecular-Weight von Willebrand Factor Multimers in Patients with Severe Aortic Stenosis After Valve Replacement. 23 10

Rapid Restoration of Thrombus Formation and High-Molecular-Weight von Willebrand Factor Multimers in Patients with Severe Aortic Stenosis After Valve Replacement. 23 10
Digital博士論文障害者向け資料あり
Yamashita, Keigo, Yagi, Hideo, Hayakawa, Masaki, Abe, Takehisa, Hayata, Yoshihiro, Yamaguchi, Naoko, Sugimoto, Mitsuhiko, Fujimura, Yoshihiro, Matsumoto, Masanori, Taniguchi, Shigeki日本動脈硬化学会2016-10-01Journal of atherosclerosis and thrombosis
National Diet Library
  • Subject HeadingAortic valve stenosis Acquired von Willebrand syndrome Thrombus formation ADAMTS13
  • Note (General)...igen (VWF:Ag), ADAMTS13 activity (ADAMTS13:AC), and plate....... In contrast, ADAMTS13:AC was 50.5%, 35.5%, 25.5%, 2...
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