Alan J. Silman (Professor of Musculoskeletal Research, Botnar Research Institute, Nuffield Department of Orthopaedics, Rheumatology and Musculoskelatal Sciences, University of Oxford, UK ), Gary J. MacFarlane (Professor of Epidemiology and Dean of Research (Life Sciences and Medicine), University of Aberdeen , UK) Tatiana Macfarlane (Epidemiologist, Medicines Monitoring Unit, University of Dundee, UK, Honorary Reader, Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, UK)Cambridge University Press2019