Protective Effects of Dietary Nasunin on Paraquat-induced Oxidative Stress in Rats

• 資料種別: 記事
• タイトル: Protective Effects of Dietary Nasunin on Paraquat-induced Oxidative Stress in Rats
• 著者・編者: Yuriko Kimura; Yumi Araki; Asako takenaka 他
• 著者標目: Yuriko Kimura; Yumi Araki; Asako takenaka
• タイトル（掲載誌）: Bioscience, Biotechnology, and Biochemistry
• 巻号年月日等（掲載誌）: 63(5) (通号 716) 1999.05
• 掲載巻: 63
• 掲載号: 5
• 掲載通号: 716
• 掲載ページ: 799～804
• 掲載年月日（W3CDTF）: 1999-05
• ISSN（掲載誌）: 0916-8451
• ISSN-L（掲載誌）: 0916-8451
• 出版事項（掲載誌）: Tokyo : Japan Society for Bioscience
• 出版地（国名コード）: JP
• 本文の言語コード: eng
• NDLC: ZR7
• 対象利用者: 一般
• 所蔵機関: 国立国会図書館
• 請求記号: Z53-G223
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館雑誌記事索引; https://ndlsearch.ndl.go.jp
• 書誌ID（NDLBibID）: 4743739; http://id.ndl.go.jp/bib/4743739
• 整理区分コード: 632

• 要約等: The preventive effects of nasunin (delphinidin-3-[4-<i>p</i>-coumaroyl-rhamnosyl(1→6)glucoside]-5-glucoside) on paraquat-induced oxidative stress were determined in rats. Decreased food intake and body weight gain and increased lung weight by feeding the rats a diet containing paraquat were clearly suppressed by supplementing nasunin to the paraquat diet. Paraquat feeding increased the concentration of thiobarbituric acid-reactive substances (TBARS) in liver lipids and the atherogenic index, and decreased the liver triacylglycerol level. These effects were also suppressed by supplementing nasunin to the paraquat diet. In addition, catalase activity in the liver mitochondrial fraction was markedly decreased by feeding the paraquat diet, this decrease being partially suppressed by supplementing the paraquat diet with nasunin. These results suggest that nasunin acted preventively against the oxidative stress <i>in vivo</i> that may have been due to active oxygen species formed through the action of paraquat.<br>
• DOI: 10.1271/bbb.63.799
• オンライン閲覧公開範囲: インターネット公開
• 連携機関・データベース: 科学技術振興機構 : J-STAGE; http://www.jstage.jst.go.jp

• 要約等: The preventive effects of nasunin (delphinidin-3-[4-<i>p</i>-coumaroyl-rhamnosyl(1→6)glucoside]-5-glucoside) on paraquat-induced oxidative stress were determined in rats. Decreased food intake and body weight gain and increased lung weight by feeding the rats a diet containing paraquat were clearly suppressed by supplementing nasunin to the paraquat diet. Paraquat feeding increased the concentration of thiobarbituric acid-reactive substances (TBARS) in liver lipids and the atherogenic index, and decreased the liver triacylglycerol level. These effects were also suppressed by supplementing nasunin to the paraquat diet. In addition, catalase activity in the liver mitochondrial fraction was markedly decreased by feeding the paraquat diet, this decrease being partially suppressed by supplementing the paraquat diet with nasunin. These results suggest that nasunin acted preventively against the oxidative stress <i>in vivo</i> that may have been due to active oxygen species formed through the action of paraquat.<br>
• DOI: 10.1271/bbb.63.799; https://doi.org/10.1271/bbb.63.799
• 関連情報（URI）: http://id.ndl.go.jp/bib/4743739; https://ndlsearch.ndl.go.jp/books/R000000004-I4743739; http://www.tandfonline.com/doi/pdf/10.1271/bbb.63.799
• 参照: Protective Effects of Boysenberry Anthocyanins on Oxidative Stress in Diabetic Rats; https://cir.nii.ac.jp/crid/1390001204453993728; Preventive Effect of Dietary Nasunin on Galactosamine-Induced Liver Injury in Rats; https://cir.nii.ac.jp/crid/1390001204456635904; シクロデキストリン包接によるナス下漬液由来ナスニン含有粉末の品質改善および機能性評価; https://cir.nii.ac.jp/crid/1390001206407216128; ラットのパラコート誘発酸化ストレスに対するビルベリー（Ｖａｃｃｉｎｉｕｍ ｍｙｒｔｉｌｌｕｓ Ｌ．）エキスの抑制効果; https://cir.nii.ac.jp/crid/1390001206408196608; ナス下漬液からナスニンおよびクロロゲン酸を含む抗酸化性粉末の調製; https://cir.nii.ac.jp/crid/1390001206408733952; 紫ニンジン色素抽出物の拘束ストレス負荷マウスに及ぼす効果; https://cir.nii.ac.jp/crid/1390001206410094848; effect of excessive intake of quercetin on the vitamin E level and antioxidative enzyme activities of mouse liver under paraquat-induced oxidative stress; https://cir.nii.ac.jp/crid/1390001206479708032; 非栄養素ポリフェノールの探索研究と生理機能解析 （平成 ２２年度日本栄養・食糧学会学会賞受賞）; https://cir.nii.ac.jp/crid/1390282681270258688; ナス果菜外果皮からのナスニンを含む天然色素素材の調製; https://cir.nii.ac.jp/crid/1390282681384844928
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; Crossref; https://www.crossref.org; PubMed; https://pubmed.ncbi.nlm.nih.gov; CiNii Articles
• 書誌ID（NDLBibID）: 4743739; http://id.ndl.go.jp/bib/4743739
• NII論文ID: 110002679567