Abnormal pontine activation in pathological laughing as shown by functional magnetic resonance imaging

• 資料種別: 文書・図像類
• タイトル: Abnormal pontine activation in pathological laughing as shown by functional magnetic resonance imaging
• 著者・編者: KOSAKA, H; OMATA, N; OMORI, M; SHIMOYAMA, T; MURATA, T; KASHIKURA, K; TAKAHASHI, T; MURAYAMA, J; YONEKURA, Y; WADA, Y
• 著者標目: KOSAKA, H; OMATA, N; OMORI, M; SHIMOYAMA, T; MURATA, T; KASHIKURA, K; TAKAHASHI, T; MURAYAMA, J; YONEKURA, Y; WADA, Y
• 出版事項: BMJ Publishing Group
• 出版年月日等: 2006-12
• 出版年（W3CDTF）: 2006-12
• タイトル（掲載誌）: Journal of neurology, neurosurgery and psychiatry
• 巻号年月日等（掲載誌）: 77 12
• 掲載巻: 77
• 掲載号: 12
• 掲載ページ: 1376-1380
• 本文の言語コード: eng
• 対象利用者: 一般
• 一般注記: To explore the aetiology of pathological laughing, a 65-year-old woman with pathological laughing was examined by 3-T functional magnetic resonance imaging (fMRI) before and after treatment with drugs. Here, we report that the patient consistently showed exaggerated pontine activation during the performance of three tasks before treatment, whereas abnormal pontine activation was no longer found after successful treatment with the selective serotonin reuptake inhibitor, paroxetine. Our findings in this first fMRI study of pathological laughing suggest that serotonergic replacement decreases the aberrant activity in a circuit that involves the pons.
• 一次資料へのリンクURL: https://u-fukui.repo.nii.ac.jp/?action=repository_action_common_download&item_id=20603&item_no=1&attribute_id=22&file_no=1
• オンライン閲覧公開範囲: 限定公開
• 関連情報（DOI）: 10.1136/jnnp.2005.073288
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 福井大学 : 福井大学学術機関リポジトリ