Low-intensity pulsed ultrasound enhances bone formation around miniscrew implants

• 資料種別: 博士論文
• タイトル: Low-intensity pulsed ultrasound enhances bone formation around miniscrew implants
• 著者・編者: Ganzorig, Khaliunaa; Kuroda, Shingo; Maeda, Yuichi; Mansjur, Karima; Sato, Minami; Nagata, Kumiko; Tanaka, Eiji
• 著者標目: Ganzorig, Khaliunaa; Kuroda, Shingo; Maeda, Yuichi; Mansjur, Karima; Sato, Minami; Nagata, Kumiko; Tanaka, Eiji
• 出版事項: Elsevier
• 出版年月日等: 2015-03-04
• 出版年（W3CDTF）: 2015-03-04
• 並列タイトル等: LIPUSはミニスクリューインプラント周囲の骨形成を促進する
• タイトル（掲載誌）: Archives of Oral Biology
• 巻号年月日等（掲載誌）: 60 6
• 掲載巻: 60
• 掲載号: 6
• 掲載ページ: 902-910
• ISSN（掲載誌）: ISSN : 0003-9969
• 授与機関名: 徳島大学
• 授与年月日: 2015-09-16
• 報告番号: 甲第2863号
• 学位: 博士（歯学）
• 本文の言語コード: eng
• 件名標目: Low-intensity pulsed ultrasound; miniscrew implant; bone formation; stainless steel and titanium
• 対象利用者: 一般
• 一般注記: Miniscrew implants (MSIs) are currently used to provide absolute anchorage in orthodontics; however, their initial stability is an issue of concern. Application of low-intensity pulsed ultrasound (LIPUS) can promote bone healing. Therefore, LIPUS application may stimulate bone formation around MSIs and enhance their initial stability. Aim. To investigate the effect of LIPUS exposure on bone formation after implantation of titanium (Ti) and stainless steel (SS) MSIs. Methods. MSIs made of Ti-6Al-4V and 316L SS were placed on rat tibiae and treated with LIPUS. The bone morphology around MSIs was evaluated by scanning electron microscopy and threedimensional micro-computed tomography. MC3T3-E1 cells cultured on Ti and SS discs were treated with LIPUS, and the temporary expression of alkaline phosphatase (ALP) was examined. Results. Bone-implant contact increased gradually from day 3 to day 14 after MSI insertion. LIPUS application increased the cortical bone density, cortical bone thickness, and cortical bone rate after implantation of Ti and SS MSIs (P < 0.05). LIPUS exposure induced ALP upregulation in MC3T3- E1 cells at day 3 (P < 0.05). Conclusion. LIPUS enhanced bone formation around Ti and SS MSIs, enhancing the initial stability of MSIs.
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
• 関連情報（DOI）: 10.1016/j.archoralbio.2015.02.014
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/10/109480/20170929143724185085/LID201509181001.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/10/109480/20170929143724536809/LID201509181002.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/10/109480/2019061017535178852/k2863_fulltext.pdf fulltext