Differences In High-Intensity Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging May Be Useful For Differentiating Glioblastoma From Brain Metastasis

• 資料種別: 博士論文
• タイトル: Differences In High-Intensity Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging May Be Useful For Differentiating Glioblastoma From Brain Metastasis
• 著者・編者: Ganbold, Mungunbagana; Harada, Masafumi; Khashbat, Delgerdalai; Abe, Takashi; Kageji, Teruyoshi; Nagahiro, Shinji
• 著者標目: Ganbold, Mungunbagana; Harada, Masafumi; Khashbat, Delgerdalai; Abe, Takashi; Kageji, Teruyoshi; Nagahiro, Shinji
• 出版事項: Faculty of Medicine Tokushima University
• 出版年月日等: 2017-02
• 出版年（W3CDTF）: 2017-02
• 並列タイトル等: arterial spin labeling法と造影T1強調像の高信号容積の違いが転移性脳腫瘍から神経膠芽腫を区別するのに有用である; ASL for distinguishing GBM from metastasis
• タイトル（掲載誌）: The Journal of Medical Investigation
• 巻号年月日等（掲載誌）: 64 1-2
• 掲載巻: 64
• 掲載号: 1-2
• 掲載ページ: 58-63
• ISSN（掲載誌）: ISSN : 1349-6867; ISSN : 1343-1420
• 授与機関名: 徳島大学
• 授与年月日: 2017-03-23
• 報告番号: 甲第3019号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: arterial spin labeling; perfusion; volumetric analysis; glioblastoma; metastasis
• 対象利用者: 一般
• 一般注記: Purpose : To determine whether differences in tumor volume between arterial spin labeling (ASL) and contrast-enhanced T1-weighted MR images (CE+T1WI) can help differentiate glioblastoma (GBM) from brain metastasis. Materials and methods : Patients with a diagnosis of GBM (n=25) or brain metastasis (n=13) were examined by both conventional and ASL MR imaging. Volumes of interest with high signal intensity on ASL and CE+T1WI were defined using three dimensional analysis software. Tumor volume difference (ASL-CE) and tumor volume ratio (ASL/CE) were obtained. Absolute maximal tumor blood flow (TBF) and TBF ratio (normalized to white matter) were also measured. The Mann-Whitney U test and receiver operating characteristic curve analysis were performed to compare measurements between the tumor groups. Results : Both tumor volume difference and tumor volume ratio were significantly higher in GBM than in metastasis. Both TBF and TBF ratio were higher for GBM than for metastasis, but the differences were not significant. Conclusion : The difference in tumor volume as measured by ASL high signal intensity and CE+T1WI might be useful for differentiating GBM from metastasis, whereas ASL-derived TBF is insufficient.
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.2152/jmi.64.58
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

https://repo.lib.tokushima-u.ac.jp/files/public/11/111082/20190807162029480965/LID201704141003.pdf fulltext

https://repo.lib.tokushima-u.ac.jp/files/public/11/111082/20190807162029805939/LID201704141004.pdf fulltext