Differences In High-Intensity Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging May Be Useful For Differentiating Glioblastoma From Brain Metastasis

• Material Type: 博士論文
• Title: Differences In High-Intensity Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging May Be Useful For Differentiating Glioblastoma From Brain Metastasis
• Author/Editor: Ganbold, Mungunbagana; Harada, Masafumi; Khashbat, Delgerdalai; Abe, Takashi; Kageji, Teruyoshi; Nagahiro, Shinji
• Author Heading: Ganbold, Mungunbagana; Harada, Masafumi; Khashbat, Delgerdalai; Abe, Takashi; Kageji, Teruyoshi; Nagahiro, Shinji
• Publication, Distribution, etc.: Faculty of Medicine Tokushima University
• Publication Date: 2017-02
• Publication Date (W3CDTF): 2017-02
• Alternative Title: arterial spin labeling法と造影T1強調像の高信号容積の違いが転移性脳腫瘍から神経膠芽腫を区別するのに有用である; ASL for distinguishing GBM from metastasis
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 64 1-2
• Volume: 64
• Issue: 1-2
• Pages: 58-63
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2017-03-23
• Dissertation Number: 甲第3019号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: arterial spin labeling; perfusion; volumetric analysis; glioblastoma; metastasis
• Target Audience: 一般
• Note (General): Purpose : To determine whether differences in tumor volume between arterial spin labeling (ASL) and contrast-enhanced T1-weighted MR images (CE+T1WI) can help differentiate glioblastoma (GBM) from brain metastasis. Materials and methods : Patients with a diagnosis of GBM (n=25) or brain metastasis (n=13) were examined by both conventional and ASL MR imaging. Volumes of interest with high signal intensity on ASL and CE+T1WI were defined using three dimensional analysis software. Tumor volume difference (ASL-CE) and tumor volume ratio (ASL/CE) were obtained. Absolute maximal tumor blood flow (TBF) and TBF ratio (normalized to white matter) were also measured. The Mann-Whitney U test and receiver operating characteristic curve analysis were performed to compare measurements between the tumor groups. Results : Both tumor volume difference and tumor volume ratio were significantly higher in GBM than in metastasis. Both TBF and TBF ratio were higher for GBM than for metastasis, but the differences were not significant. Conclusion : The difference in tumor volume as measured by ASL high signal intensity and CE+T1WI might be useful for differentiating GBM from metastasis, whereas ASL-derived TBF is insufficient.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.64.58
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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https://repo.lib.tokushima-u.ac.jp/files/public/11/111082/20190807162029480965/LID201704141003.pdf fulltext

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