Efficacy of percutaneous endoscopic gastrostomy on unplanned treatment interruption and nutritional status in patients undergoing chemoradiotherapy for advanced head and neck cancer

• 資料種別: 博士論文
• タイトル: Efficacy of percutaneous endoscopic gastrostomy on unplanned treatment interruption and nutritional status in patients undergoing chemoradiotherapy for advanced head and neck cancer
• 著者・編者: Goda, Masakazu; Jinnouchi, Osamu; Takaoka, Tsukasa; Abe, Koji; Tamura, Koichi; Nakaya, Yutaka; Furukita, Yoshihito; Takechi, Hirokazu; Tangoku, Akira; Takeda, Noriaki
• 著者標目: Goda, Masakazu; Jinnouchi, Osamu; Takaoka, Tsukasa; Abe, Koji; Tamura, Koichi; Nakaya, Yutaka; Furukita, Yoshihito; Takechi, Hirokazu; Tangoku, Akira; Takeda, Noriaki
• 出版事項: Faculty of Medicine Tokushima University
• 出版年月日等: 2015-08
• 出版年（W3CDTF）: 2015-08
• 並列タイトル等: 進行頭頸部癌に対して化学放射線療法中の患者において経皮内視鏡的胃瘻造設術が治療中断や栄養状態に及ぼす効果; Efficacy of PEG on head and neck cancer
• タイトル（掲載誌）: The Journal of Medical Investigation
• 巻号年月日等（掲載誌）: 62 3-4
• 掲載巻: 62
• 掲載号: 3-4
• 掲載ページ: 173-176
• ISSN（掲載誌）: ISSN : 1349-6867; ISSN : 1343-1420
• 授与機関名: 徳島大学
• 授与年月日: 2015-07-23
• 報告番号: 甲第2864号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: percutaneous endoscopic gastrostomy; PEG; nutritional support; chemoradiotherapy; head and neck cancer
• 対象利用者: 一般
• 一般注記: Objective : Efficacy of percutaneous endoscopic gastrostomy (PEG) on unplanned treatment interruption and nutritional status was examined in patients undergoing chemoradiotherapy (CRT) for advanced head and neck cancer. Methods :We retrospectively reviewed hospital charts of 44 patients with advanced head and neck cancer who were treated with CRT. Results : CRT-induced mucositis of grade 3 or worse and inadequate oral intake of less than one third of their usual intake developed in 33 patients who were recommended PEG placement, but not in 11 patients. Thirteen patients accepted PEG placement and then completed CRT (compliant group). However, among 20 patients who refused both PEG and nasogastoric tube (NGT) placements (non-compliant group), 10 required unplanned interruptions of CRT at a radiation dose around 30-40 Gy (UI-CRT group) while 10 others could complete CRT without interruption (C-CRT group) CRT. Total serum protein levels were significantly decreased after CRT in all patients. Discussion : It is suggested that therapeutic PEG placement is useful for preventing unplanned interruption of CRT in patients with advanced head and neck cancer. After severe mucositis and inadequate oral intake have developed during CRT, PEG placement should be considered before the radiation therapy dose of 30 Gy.
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.2152/jmi.62.173
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/11/111274/20190722162825134809/LID201508041003.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/111274/20190722163032259805/LID201510261013.pdf fulltext