Efficacy of percutaneous endoscopic gastrostomy on unplanned treatment interruption and nutritional status in patients undergoing chemoradiotherapy for advanced head and neck cancer

• Material Type: 博士論文
• Title: Efficacy of percutaneous endoscopic gastrostomy on unplanned treatment interruption and nutritional status in patients undergoing chemoradiotherapy for advanced head and neck cancer
• Author/Editor: Goda, Masakazu; Jinnouchi, Osamu; Takaoka, Tsukasa; Abe, Koji; Tamura, Koichi; Nakaya, Yutaka; Furukita, Yoshihito; Takechi, Hirokazu; Tangoku, Akira; Takeda, Noriaki
• Author Heading: Goda, Masakazu; Jinnouchi, Osamu; Takaoka, Tsukasa; Abe, Koji; Tamura, Koichi; Nakaya, Yutaka; Furukita, Yoshihito; Takechi, Hirokazu; Tangoku, Akira; Takeda, Noriaki
• Publication, Distribution, etc.: Faculty of Medicine Tokushima University
• Publication Date: 2015-08
• Publication Date (W3CDTF): 2015-08
• Alternative Title: 進行頭頸部癌に対して化学放射線療法中の患者において経皮内視鏡的胃瘻造設術が治療中断や栄養状態に及ぼす効果; Efficacy of PEG on head and neck cancer
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 62 3-4
• Volume: 62
• Issue: 3-4
• Pages: 173-176
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2015-07-23
• Dissertation Number: 甲第2864号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: percutaneous endoscopic gastrostomy; PEG; nutritional support; chemoradiotherapy; head and neck cancer
• Target Audience: 一般
• Note (General): Objective : Efficacy of percutaneous endoscopic gastrostomy (PEG) on unplanned treatment interruption and nutritional status was examined in patients undergoing chemoradiotherapy (CRT) for advanced head and neck cancer. Methods :We retrospectively reviewed hospital charts of 44 patients with advanced head and neck cancer who were treated with CRT. Results : CRT-induced mucositis of grade 3 or worse and inadequate oral intake of less than one third of their usual intake developed in 33 patients who were recommended PEG placement, but not in 11 patients. Thirteen patients accepted PEG placement and then completed CRT (compliant group). However, among 20 patients who refused both PEG and nasogastoric tube (NGT) placements (non-compliant group), 10 required unplanned interruptions of CRT at a radiation dose around 30-40 Gy (UI-CRT group) while 10 others could complete CRT without interruption (C-CRT group) CRT. Total serum protein levels were significantly decreased after CRT in all patients. Discussion : It is suggested that therapeutic PEG placement is useful for preventing unplanned interruption of CRT in patients with advanced head and neck cancer. After severe mucositis and inadequate oral intake have developed during CRT, PEG placement should be considered before the radiation therapy dose of 30 Gy.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.62.173
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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