Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons

• 資料種別: 博士論文
• タイトル: Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons
• 著者・編者: Hioka, Akemi; Tada, Yoshiteru; Kitazato, Keiko; Kanematsu, Yasuhisa; Mizobuchi, Yoshifumi; Mure, Hideo; Shimada, Kenji; Okazaki, Toshiyuki; Korai, Masaaki; Akazawa, Naoki; Matsumoto, Yuki; Harada, Masafumi; Takagi, Yasushi; Nagahiro, Shinji
• 著者標目: Hioka, Akemi; Tada, Yoshiteru; Kitazato, Keiko; Kanematsu, Yasuhisa; Mizobuchi, Yoshifumi; Mure, Hideo; Shimada, Kenji; Okazaki, Toshiyuki; Korai, Masaaki; Akazawa, Naoki; Matsumoto, Yuki; Harada, Masafumi; Takagi, Yasushi; Nagahiro, Shinji
• 出版事項: Elsevier
• 出版年月日等: 2018-10-11
• 出版年（W3CDTF）: 2018-10-11
• 並列タイトル等: 亜急性期脳卒中患者および健常者における歩行観察時のミラーニューロンシステムの活性化
• タイトル（掲載誌）: Journal of Clinical Neuroscience
• 巻号年月日等（掲載誌）: 60
• 掲載巻: 60
• 掲載ページ: 79-83
• ISSN（掲載誌）: ISSN : 0967-5868
• 授与機関名: 徳島大学
• 授与年月日: 2019-01-24
• 報告番号: 甲第3249号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: gait observation; mirror neuron system; stroke; fMRI
• 対象利用者: 一般
• 一般注記: The observation of walking improves gait ability in chronic stroke survivors. It has also been suggested that activation of the mirror neuron system contributes to this effect. However, activation of the mirror neuron system during gait observation has not yet been assessed in sub-acute stroke patients. The objective of this study was to clarify the activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons. In this study, we sequentially enrolled five sub-acute stroke patients who had undergone gait training and nine healthy persons. We used fMRI to detect neuronal activation during gait observation. During the observation period in the stroke group, neural activity in the left inferior parietal lobule, right and left inferior frontal gyrus was significantly higher than during the rest period. In the healthy group, neural activity in the left inferior parietal lobule, left inferior frontal gyrus, left middle frontal gyrus, left superior temporal lobule and right and left middle temporal gyrus was significantly higher than during the rest period. The results indicate that the mirror neuron system was activated during gait observation in sub-acute stroke patients who had undergone gait training and also in healthy persons. Our findings suggest that gait observation treatment may provide a promising therapeutic strategy in sub-acute stroke patients who have experienced gait training.
• 記録形式（IMT）: application/pdf
• 一次資料へのリンクURL: fulltext; http://repo.lib.tokushima-u.ac.jp/files/public/11/113267/20190422100829682499/k3249_abstract_review.pdf; http://repo.lib.tokushima-u.ac.jp/files/public/11/113267/20190422164011708234/k3249_fulltext.pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1016/j.jocn.2018.09.035
• 掲載誌（NCID）: AA10958444; https://ci.nii.ac.jp/ncid/AA10958444
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ