Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons

• Material Type: 博士論文
• Title: Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons
• Author/Editor: Hioka, Akemi; Tada, Yoshiteru; Kitazato, Keiko; Kanematsu, Yasuhisa; Mizobuchi, Yoshifumi; Mure, Hideo; Shimada, Kenji; Okazaki, Toshiyuki; Korai, Masaaki; Akazawa, Naoki; Matsumoto, Yuki; Harada, Masafumi; Takagi, Yasushi; Nagahiro, Shinji
• Author Heading: Hioka, Akemi; Tada, Yoshiteru; Kitazato, Keiko; Kanematsu, Yasuhisa; Mizobuchi, Yoshifumi; Mure, Hideo; Shimada, Kenji; Okazaki, Toshiyuki; Korai, Masaaki; Akazawa, Naoki; Matsumoto, Yuki; Harada, Masafumi; Takagi, Yasushi; Nagahiro, Shinji
• Publication, Distribution, etc.: Elsevier
• Publication Date: 2018-10-11
• Publication Date (W3CDTF): 2018-10-11
• Alternative Title: 亜急性期脳卒中患者および健常者における歩行観察時のミラーニューロンシステムの活性化
• Periodical title: Journal of Clinical Neuroscience
• No. or year of volume/issue: 60
• Volume: 60
• Pages: 79-83
• ISSN (Periodical Title): ISSN : 0967-5868
• Degree grantor/type: 徳島大学
• Date Granted: 2019-01-24
• Dissertation Number: 甲第3249号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: gait observation; mirror neuron system; stroke; fMRI
• Target Audience: 一般
• Note (General): The observation of walking improves gait ability in chronic stroke survivors. It has also been suggested that activation of the mirror neuron system contributes to this effect. However, activation of the mirror neuron system during gait observation has not yet been assessed in sub-acute stroke patients. The objective of this study was to clarify the activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons. In this study, we sequentially enrolled five sub-acute stroke patients who had undergone gait training and nine healthy persons. We used fMRI to detect neuronal activation during gait observation. During the observation period in the stroke group, neural activity in the left inferior parietal lobule, right and left inferior frontal gyrus was significantly higher than during the rest period. In the healthy group, neural activity in the left inferior parietal lobule, left inferior frontal gyrus, left middle frontal gyrus, left superior temporal lobule and right and left middle temporal gyrus was significantly higher than during the rest period. The results indicate that the mirror neuron system was activated during gait observation in sub-acute stroke patients who had undergone gait training and also in healthy persons. Our findings suggest that gait observation treatment may provide a promising therapeutic strategy in sub-acute stroke patients who have experienced gait training.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1016/j.jocn.2018.09.035
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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