PROTECTIVE EFFECTS OF LOW-INTENSITY PULSED ULTRASOUND ON MANDIBULAR CONDYLAR CARTILAGE EXPOSED TO MECHANICAL OVERLOADING

• 資料種別: 博士論文
• タイトル: PROTECTIVE EFFECTS OF LOW-INTENSITY PULSED ULTRASOUND ON MANDIBULAR CONDYLAR CARTILAGE EXPOSED TO MECHANICAL OVERLOADING
• 著者・編者: Fujita, Mutsumi; Sato-Shigeta, Minami; Mori, Hiroki; Iwasa, Akihiko; Kawai, Nobuhiko; Hassan, Ali H.; Tanaka, Eiji
• 著者標目: Fujita, Mutsumi; Sato-Shigeta, Minami; Mori, Hiroki; Iwasa, Akihiko; Kawai, Nobuhiko; Hassan, Ali H.; Tanaka, Eiji
• 出版事項: Elsevier B.V.|World Federation for Ultrasound in Medicine and Biology
• 出版年月日等: 2019-02-04
• 出版年（W3CDTF）: 2019-02-04
• 並列タイトル等: 過剰な機械的負荷に曝された下顎頭軟骨に対する低出力パルス超音波照射の保護効果; LIPUS effect on osteoarthritic TMJs
• タイトル（掲載誌）: Ultrasound in Medicine and Biology
• 巻号年月日等（掲載誌）: 45 4
• 掲載巻: 45
• 掲載号: 4
• 掲載ページ: 944-953
• ISSN（掲載誌）: ISSN : 0301-5629
• 授与機関名: 徳島大学
• 授与年月日: 2019-03-22
• 報告番号: 甲第3283号
• 学位: 博士（歯学）
• 本文の言語コード: eng
• 件名標目: Temporomandibular joint; Osteoarthritis; Mandibular condyle; Low-intensity pulsed ultrasound; Rats
• 対象利用者: 一般
• 一般注記: The aim of this study was to assess the effect of low-intensity pulsed ultrasound (LIPUS) application on rat temporomandibular joints (TMJs) with early-stage of osteoarthritis-like conditions induced by mechanical overloading. Fifteen-week-old male Wistar rats were divided into two experimental groups and a control group (n = 10 each). Both TMJs of all rats in one experimental group were subjected to mechanical overloading for 5 d, and those in the other experimental group were exposed to LIPUS for 20 min/d after overloading. Condyles were assessed using micro-computed tomography, histology and histomorphometry. LIPUS treatment attenuated cartilage degeneration, decreased the number of osteoclastic cells and restored the expression of aggrecan after an initial decrease induced by mechanical overloading. These results indicate that LIPUS may have a protective effect on the early progression of TMJ osteoarthritis.
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1016/j.ultrasmedbio.2018.12.006
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/11/113373/20190610112524724308/k3283_abstract.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/113373/20190610112525362508/k3283_review.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/113373/20190610112525646021/k3283_fulltext.pdf fulltext