PROTECTIVE EFFECTS OF LOW-INTENSITY PULSED ULTRASOUND ON MANDIBULAR CONDYLAR CARTILAGE EXPOSED TO MECHANICAL OVERLOADING

• Material Type: 博士論文
• Title: PROTECTIVE EFFECTS OF LOW-INTENSITY PULSED ULTRASOUND ON MANDIBULAR CONDYLAR CARTILAGE EXPOSED TO MECHANICAL OVERLOADING
• Author/Editor: Fujita, Mutsumi; Sato-Shigeta, Minami; Mori, Hiroki; Iwasa, Akihiko; Kawai, Nobuhiko; Hassan, Ali H.; Tanaka, Eiji
• Author Heading: Fujita, Mutsumi; Sato-Shigeta, Minami; Mori, Hiroki; Iwasa, Akihiko; Kawai, Nobuhiko; Hassan, Ali H.; Tanaka, Eiji
• Publication, Distribution, etc.: Elsevier B.V.|World Federation for Ultrasound in Medicine and Biology
• Publication Date: 2019-02-04
• Publication Date (W3CDTF): 2019-02-04
• Alternative Title: 過剰な機械的負荷に曝された下顎頭軟骨に対する低出力パルス超音波照射の保護効果; LIPUS effect on osteoarthritic TMJs
• Periodical title: Ultrasound in Medicine and Biology
• No. or year of volume/issue: 45 4
• Volume: 45
• Issue: 4
• Pages: 944-953
• ISSN (Periodical Title): ISSN : 0301-5629
• Degree grantor/type: 徳島大学
• Date Granted: 2019-03-22
• Dissertation Number: 甲第3283号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: Temporomandibular joint; Osteoarthritis; Mandibular condyle; Low-intensity pulsed ultrasound; Rats
• Target Audience: 一般
• Note (General): The aim of this study was to assess the effect of low-intensity pulsed ultrasound (LIPUS) application on rat temporomandibular joints (TMJs) with early-stage of osteoarthritis-like conditions induced by mechanical overloading. Fifteen-week-old male Wistar rats were divided into two experimental groups and a control group (n = 10 each). Both TMJs of all rats in one experimental group were subjected to mechanical overloading for 5 d, and those in the other experimental group were exposed to LIPUS for 20 min/d after overloading. Condyles were assessed using micro-computed tomography, histology and histomorphometry. LIPUS treatment attenuated cartilage degeneration, decreased the number of osteoclastic cells and restored the expression of aggrecan after an initial decrease induced by mechanical overloading. These results indicate that LIPUS may have a protective effect on the early progression of TMJ osteoarthritis.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1016/j.ultrasmedbio.2018.12.006
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

Table of Contents

http://repo.lib.tokushima-u.ac.jp/files/public/11/113373/20190610112524724308/k3283_abstract.pdf fulltext

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