Drug-induced interstitial pneumonia during perioperative chemotherapy for breast cancer

• 資料種別: 博士論文
• タイトル: Drug-induced interstitial pneumonia during perioperative chemotherapy for breast cancer
• 著者・編者: Ikeuchi, Mayumi; Hino, Naoki; Nishisyo, Aya; Aoyama, Mariko; Kanematsu, Miyuki; Inoue, Hiroaki; Sasa, Soichiro; Inui, Tomohiro; Miyamoto, Naoki; Okumura, Kazumasa; Takizawa, Hiromitsu
• 著者標目: Ikeuchi, Mayumi; Hino, Naoki; Nishisyo, Aya; Aoyama, Mariko; Kanematsu, Miyuki; Inoue, Hiroaki; Sasa, Soichiro; Inui, Tomohiro; Miyamoto, Naoki; Okumura, Kazumasa; Takizawa, Hiromitsu
• 出版事項: Tokushima University Faculty of Medicine
• 出版年月日等: 2022-02
• 出版年（W3CDTF）: 2022-02
• 並列タイトル等: 乳癌周術期化学療法中に薬剤性間質性肺炎を発症した症例の検討; DIP during perioperative chemotherapy
• タイトル（掲載誌）: The Journal of Medical Investigation
• 巻号年月日等（掲載誌）: 69 1-2
• 掲載巻: 69
• 掲載号: 1-2
• 掲載ページ: 107-111
• ISSN（掲載誌）: ISSN : 1349-6867; ISSN : 1343-1420
• 授与機関名: 徳島大学
• 授与年月日: 2022-09-22
• 報告番号: 甲第3658号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: breast cancer; Drug-induced interstitial pneumonia; perioperative chemotherapy
• 対象利用者: 一般
• 一般注記: Purpose : Drug-induced interstitial pneumonia (DIP) that occurs during chemotherapy for breast cancer is a rare but a serious adverse event. Treatments of DIP requires interruption of breast cancer treatment, which may affect the patient’s prognosis. However, there are few reports which discuss DIP during breast cancer treatments. Purpose of this report is to make clear how DIP occurred and influenced breast cancer treatment in our hospital. Patients and Methods : A total of 74 patients who started perioperative chemotherapy in Tokushima Municipal Hospital for breast cancer from January 2019 to December 2020 were evaluated for DIP. Patients’ and tumors’ characteristics, and regimens which caused DIP were investigated. The clinical courses of the DIP patients were also followed up. Results : Twelve of the 74 patients developed DIP. All 12 patients had histories of cyclophosphamide administration ; however, the causative drug could not be determined. Ten of the 12 patients were treated with steroids, and all the patients recovered ultimately from the interstitial pneumonia. While chemotherapy was administered in six patients after mild DIP, no relapse of pneumonia was observed. Conclusion : DIP during perioperative chemotherapy for breast cancer was resolved with appropriate treatment. Patients were able to resume breast cancer treatment with minimal interruption.
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.2152/jmi.69.107
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/11/117020/20221019163838895019/k3658_abstract.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/117020/20221019163839248054/k3658_review.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/117020/20221019163839521768/k3658_fulltext.pdf fulltext