Rat Endothelial Cell Attachment, Behavior and Gene Expression on NaOH-treated Titanium Surfaces

• 資料種別: 博士論文
• タイトル: Rat Endothelial Cell Attachment, Behavior and Gene Expression on NaOH-treated Titanium Surfaces
• 著者・編者: 中野, 容子
• 著者標目: 中野, 容子
• 出版事項: Japanese Association of Regenerative Dentistry
• 並列タイトル等: 水酸化ナトリウム水溶液によりチタン表面に析出したナノ構造がラット血管内皮細胞の初期接着および遺伝子発現に与える影響について
• 授与機関名: 大阪歯科大学
• 授与年月日: 2014-03-07
• 報告番号: 甲第737号
• 学位: 博士（歯学）
• 本文の言語コード: eng
• 件名標目: aortic endothelial cells; titanium; nanostructures; wound healing
• 対象利用者: 一般
• 一般注記: The aim of this study was to evaluate the influence of nanostructures on the surface of titanium, titanium nanosheets (TNS), on the initial attachment, proliferation, and gene expression of various functional factors by rat aortic endothelial cells (RAEC) involved in wound healing. We found that the initial attachment and proliferation of RAECs after 15, 30, 45, 60, and 120 min of culture were increased on titanium surfaces modified with TNS. We also found that the expression of intercellular adhesion molecule 1, von Willebrand, and thrombomodulin transcription factors were elevated in samples containing a TNS-modified disk in compared with unmodified titanium disks during the early stages of wound healing. Our results suggest that nanostructures on titanium surfaces stimulate RAECs to upregulate expression of angiogenic factors and adhesion molecule genes, which play an essential role in controlling inflammation and revascularization during wound healing after implantation.; 2013
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: CC BY-NC-ND
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 大阪歯科大学 : 大阪歯科大学学術リポジトリ

目次

https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=60&item_no=1&attribute_id=20&file_no=1 fulltext

https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=60&item_no=1&attribute_id=20&file_no=2 fulltext