並列タイトル等新規バイオアクティブガラス配合覆髄剤の有効性の検討
一般注記Purpose: We measured the Knoop hardness of demineralized dentin over time using Cariotester to deter- mine the effectiveness of several types of pulp-capping agent for atraumatic indirect pulp capping(AIPC). Methods: Extracted human molars were used to prepare dentin samples with a diameter of 10 mm and thickness of 2 mm. Sound dentin samples were immersed in lactic acid solution and were regarded as demin- eralized when the value obtained using Cariotester was approximately 20 KNH. A new bioactive glass-com- pounded pulp-capping agent(Shofu), Bio MTA cement(J. Morita), and NEX MTA cement(GC)were used as the pulp-capping agents in the present study. Each pulp-capping agent was applied to the surface of demineralized dentin and covered with Base cement. After the Base cement solidified, pulp-capped dentin samples and controls were divided into two groups: those placed in a container with 100% humidity and those immersed in remineralization solution, and stored at 37°C in a thermostatic chamber for l month and 3 months. The hardness of the capping agent-applied region was then measured. Data were analyzed using a one-way analysis of variance and Tukey’s test(α=0.001). Pulp-capping agent-applied surfaces were also observed under SEM. Results: The hardness of demineralized dentin increased with the application of a new bioactive glass-com- pounded pulp-capping agent, Bio MTA cement, and NEX MTA cement, and mineralized substance-like aggregates were deposited on the surface of and between collagen fibers. It is assumed that the demineral- ized dentin had remineralized as the bioactive glass-compounded pulp-capping agent was pasted. Conclusion: These results indicate the effectiveness of the new bioactive glass-compounded pulp-capping agent in the remineralization of demineralized dentin.
2019年度
連携機関・データベース国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）