Study on Rehardening of Demineralized Dentin with the New Pulp-capping Agents Containing Bioactive Glass

• Material Type: 博士論文
• Title: Study on Rehardening of Demineralized Dentin with the New Pulp-capping Agents Containing Bioactive Glass
• Author/Editor: 澤井, 健司郎
• Author Heading: 澤井, 健司郎
• Alternative Title: 新規バイオアクティブガラス配合覆髄剤の有効性の検討
• Degree grantor/type: 大阪歯科大学
• Date Granted: 2020-03-06
• Dissertation Number: 甲第861号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: Knoop hardness; pulp-capping agent; remineralization
• Target Audience: 一般
• Note (General): Purpose: We measured the Knoop hardness of demineralized dentin over time using Cariotester to deter- mine the effectiveness of several types of pulp-capping agent for atraumatic indirect pulp capping(AIPC). Methods: Extracted human molars were used to prepare dentin samples with a diameter of 10 mm and thickness of 2 mm. Sound dentin samples were immersed in lactic acid solution and were regarded as demin- eralized when the value obtained using Cariotester was approximately 20 KNH. A new bioactive glass-com- pounded pulp-capping agent(Shofu), Bio MTA cement(J. Morita), and NEX MTA cement(GC)were used as the pulp-capping agents in the present study. Each pulp-capping agent was applied to the surface of demineralized dentin and covered with Base cement. After the Base cement solidified, pulp-capped dentin samples and controls were divided into two groups: those placed in a container with 100% humidity and those immersed in remineralization solution, and stored at 37°C in a thermostatic chamber for l month and 3 months. The hardness of the capping agent-applied region was then measured. Data were analyzed using a one-way analysis of variance and Tukey’s test(α=0.001). Pulp-capping agent-applied surfaces were also observed under SEM. Results: The hardness of demineralized dentin increased with the application of a new bioactive glass-com- pounded pulp-capping agent, Bio MTA cement, and NEX MTA cement, and mineralized substance-like aggregates were deposited on the surface of and between collagen fibers. It is assumed that the demineral- ized dentin had remineralized as the bioactive glass-compounded pulp-capping agent was pasted. Conclusion: These results indicate the effectiveness of the new bioactive glass-compounded pulp-capping agent in the remineralization of demineralized dentin.; 2019年度
• Access Restrictions: インターネット公開
• Rights (production): CC BY-NC-ND
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ

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