並列タイトル等Studies on the molecular evolution (affinity maturation) of antibodies: unexpected encounter
一般注記Antibodies are unique proteins in that they improve their affinity for antigens during
antibody responses. This process termed “affinity maturation” is the result of random
hypermutation of immunoglobulin genes in B cells followed by selection of the clones that acquired
high-affinity antibodies. However, what mechanisms are responsible for the induction of
hypermutation and the subsequent B cell selection in germinal centers has remained unknown in
many respects. I would like to talk about our long-lasting studies on these immunologic
mechanisms focusing on the functional role of follicular dendritic cells
一次資料へのリンクURLhttps://ousar.lib.okayama-u.ac.jp/files/public/5/53479/20160528121239467735/poalas_031_002_003.pdf
連携機関・データベース国立情報学研究所 : 学術機関リポジトリデータベース(IRDB)(機関リポジトリ)