抗体の分子進化（親和性成熟）の研究： 面白い結果は思いがけなく訪れる

• Material Type: 文書・図像類
• Title: 抗体の分子進化（親和性成熟）の研究： 面白い結果は思いがけなく訪れる
• Author/Editor: 大森, 斉
• Author Heading: 大森, 斉
• Publication, Distribution, etc.: 岡山実験動物研究会
• Publication Date: 2015-04
• Publication Date (W3CDTF): 2015-04
• Alternative Title: Studies on the molecular evolution (affinity maturation) of antibodies: unexpected encounter
• Periodical title: 岡山実験動物研究会報
• No. or year of volume/issue: 31
• Volume: 31
• Pages: 2-3
• Text Language Code: jpn
• Target Audience: 一般
• Note (General): Antibodies are unique proteins in that they improve their affinity for antigens during antibody responses. This process termed “affinity maturation” is the result of random hypermutation of immunoglobulin genes in B cells followed by selection of the clones that acquired high-affinity antibodies. However, what mechanisms are responsible for the induction of hypermutation and the subsequent B cell selection in germinal centers has remained unknown in many respects. I would like to talk about our long-lasting studies on these immunologic mechanisms focusing on the functional role of follicular dendritic cells
• Source: https://ousar.lib.okayama-u.ac.jp/files/public/5/53479/20160528121239467735/poalas_031_002_003.pdf
• Access Restrictions: 限定公開
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 岡山大学 : 岡山大学学術成果リポジトリ