Reduced prefrontal hemodynamic response in pediatric obsessive-compulsive disorder as measured by near-infrared spectroscopy.

• 資料種別: 博士論文
• タイトル: Reduced prefrontal hemodynamic response in pediatric obsessive-compulsive disorder as measured by near-infrared spectroscopy.
• 著者・編者: Ota, Toyosaku; Iida, Junzo; Sawada, Masayuki; Suehiro, Yuko; Yamamuro, Kazuhiko; Matsuura, Hiroki; Tanaka, Shohei; Kishimoto, Naoko; Negoro, Hideki; Kishimoto, Toshifumi
• 著者標目: Ota, Toyosaku; Iida, Junzo; Sawada, Masayuki; Suehiro, Yuko; Yamamuro, Kazuhiko; Matsuura, Hiroki; Tanaka, Shohei; Kishimoto, Naoko; Negoro, Hideki; Kishimoto, Toshifumi
• 出版事項: Springer US
• 出版年月日等: 2013-04
• 出版年（W3CDTF）: 2013-04
• タイトル（掲載誌）: Child psychiatry and human development
• 巻号年月日等（掲載誌）: 44 2
• 掲載巻: 44
• 掲載号: 2
• 掲載ページ: 265-277
• ISSN（掲載誌）: ISSN : 0009-398X
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2013-07-22
• 報告番号: 乙第1315号
• 学位: 博士（医学）
• 本文の言語コード: und
• 件名標目: Pediatric obsessive–compulsive disorder; Near-infrared spectroscopy; Functional neuroimaging study; Prefrontal hemodynamic response
• 対象利用者: 一般
• 一般注記: type:Thesis; Recent developments in near-infrared spectroscopy (NIRS) have enabled non-invasive clarification of brain functions in psychiatric disorders. Functional neuroimaging studies of patients with obsessive–compulsive disorder (OCD) have suggested that the frontal cortex and subcortical structures may play a role in the pathophysiology of the disorder. Twelve treatment-naïve children with OCD and 12 age- and sex-matched healthy control subjects participated in the present study after giving consent. The relative concentrations of oxyhemoglobin (oxy-Hb) were measured with prefrontal probes every 0.1 s during the Stroop color-word task, using 24-channel NIRS machines. During the Stroop color-word task, the oxy-Hb changes in the OCD group were significantly smaller than those in the control group in the prefrontal cortex, especially in the frontopolar cortex. The present study suggests that children with OCD have reduced prefrontal hemodynamic response as measured by NIRS.; 博士（医学）・乙第1315号・平成25年7月22日; identifier:Child psychiatry and human development Vol.44 No.2 p.265-277; identifier:0009398X; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2637; identifier:Child psychiatry and human development, 44(2): 265-277
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1007/s10578-012-0323-0
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/1/01%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/2/02%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/4/03%e6%9c%ac%e6%96%87.pdf fulltext