Reduced prefrontal hemodynamic response in pediatric obsessive-compulsive disorder as measured by near-infrared spectroscopy.

• Material Type: 博士論文
• Title: Reduced prefrontal hemodynamic response in pediatric obsessive-compulsive disorder as measured by near-infrared spectroscopy.
• Author/Editor: Ota, Toyosaku; Iida, Junzo; Sawada, Masayuki; Suehiro, Yuko; Yamamuro, Kazuhiko; Matsuura, Hiroki; Tanaka, Shohei; Kishimoto, Naoko; Negoro, Hideki; Kishimoto, Toshifumi
• Author Heading: Ota, Toyosaku; Iida, Junzo; Sawada, Masayuki; Suehiro, Yuko; Yamamuro, Kazuhiko; Matsuura, Hiroki; Tanaka, Shohei; Kishimoto, Naoko; Negoro, Hideki; Kishimoto, Toshifumi
• Publication, Distribution, etc.: Springer US
• Publication Date: 2013-04
• Publication Date (W3CDTF): 2013-04
• Periodical title: Child psychiatry and human development
• No. or year of volume/issue: 44 2
• Volume: 44
• Issue: 2
• Pages: 265-277
• ISSN (Periodical Title): ISSN : 0009-398X
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2013-07-22
• Dissertation Number: 乙第1315号
• Degree Type: 博士（医学）
• Text Language Code: und
• Subject Heading: Pediatric obsessive–compulsive disorder; Near-infrared spectroscopy; Functional neuroimaging study; Prefrontal hemodynamic response
• Target Audience: 一般
• Note (General): type:Thesis; Recent developments in near-infrared spectroscopy (NIRS) have enabled non-invasive clarification of brain functions in psychiatric disorders. Functional neuroimaging studies of patients with obsessive–compulsive disorder (OCD) have suggested that the frontal cortex and subcortical structures may play a role in the pathophysiology of the disorder. Twelve treatment-naïve children with OCD and 12 age- and sex-matched healthy control subjects participated in the present study after giving consent. The relative concentrations of oxyhemoglobin (oxy-Hb) were measured with prefrontal probes every 0.1 s during the Stroop color-word task, using 24-channel NIRS machines. During the Stroop color-word task, the oxy-Hb changes in the OCD group were significantly smaller than those in the control group in the prefrontal cortex, especially in the frontopolar cortex. The present study suggests that children with OCD have reduced prefrontal hemodynamic response as measured by NIRS.; 博士（医学）・乙第1315号・平成25年7月22日; identifier:Child psychiatry and human development Vol.44 No.2 p.265-277; identifier:0009398X; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2637; identifier:Child psychiatry and human development, 44(2): 265-277
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s10578-012-0323-0
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

Table of Contents

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/1/01%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/2/02%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2637/4/03%e6%9c%ac%e6%96%87.pdf fulltext