A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer.

• 資料種別: 博士論文
• タイトル: A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer.
• 著者・編者: Nakamura, Kota; Sho, Masayuki; Akahori, Takahiro; Nagai, Minako; Nishiwada, Satoshi; Nakagawa, Kenji; Tanaka, Toshihiro; Kichikawa, Kimihiko; Tamamoto, Tetsuro; Hasegawa, Masatoshi; Mitoro, Akira; Yoshiji, Hitoshi; Ikeda, Naoya
• 著者標目: Nakamura, Kota; Sho, Masayuki; Akahori, Takahiro; Nagai, Minako; Nishiwada, Satoshi; Nakagawa, Kenji; Tanaka, Toshihiro; Kichikawa, Kimihiko; Tamamoto, Tetsuro; Hasegawa, Masatoshi; Mitoro, Akira; Yoshiji, Hitoshi; Ikeda, Naoya
• 出版事項: Springer Nature
• 出版年月日等: 2019-02
• 出版年（W3CDTF）: 2019-02
• 並列タイトル等: 切除可能膵癌に対する術前化学放射線療法における胆道プラスチックステント及びメタルステントの比較
• タイトル（掲載誌）: World journal of surgery
• 巻号年月日等（掲載誌）: 43 2
• 掲載巻: 43
• 掲載号: 2
• 掲載ページ: 642-648
• ISSN（掲載誌）: ISSN : 0364-2313
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2020-09-30
• 報告番号: 乙第1467号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 対象利用者: 一般
• 一般注記: type:Thesis; Background: The optimal stent type in patients receiving preoperative neoadjuvant chemoradiotherapy (NACRT) is uncertain. The present study aimed to compare the clinical effectiveness of biliary metallic stent (MS) and plastic stent (PS) in patients undergoing preoperative NACRT for resectable pancreatic cancer. Methods: This retrospective study included 43 patients who required either biliary MS or PS before initiating NACRT for resectable or borderline resectable pancreatic head cancer. Seventeen patients had MS (MS group), while 23 patients had PS (PS group). All patients received preoperative NACRT, including gemcitabine and concomitant three-dimensional radiation of 54 Gy, and underwent pancreatectomy. Stent patency, surgery postponement, postoperative outcomes, and cost-effectiveness were compared between these groups. Results: There were no significant differences in baseline demographic or tumor characteristics between the groups. Stent patency was significantly longer in the MS group than in the PS group (p = 0.042). There were no differences in time to surgery, intraoperative characteristics, surgical complications, margin positivity, and pathological response between the groups. Furthermore, the medical cost of maintenance of biliary drainage during NACRT was similar between the groups. Conclusions: MS placement compared to PS in patients receiving preoperative NACRT provided no significant benefits during the postoperative course of pancreatectomy. However, MS placement was associated with long stent patency while showing no economic disadvantage. Therefore, MS placement may be recommended in patients receiving preoperative NACRT for resectable pancreatic cancer.; 博士（医学）・乙第1467号・令和2年9月30日; © Société Internationale de Chirurgie 2018; This is a post-peer-review, pre-copyedit version of an article published in World journal of surgery. The final authenticated version is available online at: https://doi.org/10.1007/s00268-018-4820-6.; identifier:World journal of surgery Vol.43 No.2 p.642-648 (2019 Feb); identifier:03642313; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3783; identifier:World journal of surgery, 43(2): 642-648
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1007/s00268-018-4820-6
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/1/01%e4%b9%991467%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/2/02%e4%b9%991467%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/3/03%e4%b9%991467%e6%9c%ac%e6%96%87.pdf fulltext