A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer.

• Material Type: 博士論文
• Title: A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer.
• Author/Editor: Nakamura, Kota; Sho, Masayuki; Akahori, Takahiro; Nagai, Minako; Nishiwada, Satoshi; Nakagawa, Kenji; Tanaka, Toshihiro; Kichikawa, Kimihiko; Tamamoto, Tetsuro; Hasegawa, Masatoshi; Mitoro, Akira; Yoshiji, Hitoshi; Ikeda, Naoya
• Author Heading: Nakamura, Kota; Sho, Masayuki; Akahori, Takahiro; Nagai, Minako; Nishiwada, Satoshi; Nakagawa, Kenji; Tanaka, Toshihiro; Kichikawa, Kimihiko; Tamamoto, Tetsuro; Hasegawa, Masatoshi; Mitoro, Akira; Yoshiji, Hitoshi; Ikeda, Naoya
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2019-02
• Publication Date (W3CDTF): 2019-02
• Alternative Title: 切除可能膵癌に対する術前化学放射線療法における胆道プラスチックステント及びメタルステントの比較
• Periodical title: World journal of surgery
• No. or year of volume/issue: 43 2
• Volume: 43
• Issue: 2
• Pages: 642-648
• ISSN (Periodical Title): ISSN : 0364-2313
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2020-09-30
• Dissertation Number: 乙第1467号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Target Audience: 一般
• Note (General): type:Thesis; Background: The optimal stent type in patients receiving preoperative neoadjuvant chemoradiotherapy (NACRT) is uncertain. The present study aimed to compare the clinical effectiveness of biliary metallic stent (MS) and plastic stent (PS) in patients undergoing preoperative NACRT for resectable pancreatic cancer. Methods: This retrospective study included 43 patients who required either biliary MS or PS before initiating NACRT for resectable or borderline resectable pancreatic head cancer. Seventeen patients had MS (MS group), while 23 patients had PS (PS group). All patients received preoperative NACRT, including gemcitabine and concomitant three-dimensional radiation of 54 Gy, and underwent pancreatectomy. Stent patency, surgery postponement, postoperative outcomes, and cost-effectiveness were compared between these groups. Results: There were no significant differences in baseline demographic or tumor characteristics between the groups. Stent patency was significantly longer in the MS group than in the PS group (p = 0.042). There were no differences in time to surgery, intraoperative characteristics, surgical complications, margin positivity, and pathological response between the groups. Furthermore, the medical cost of maintenance of biliary drainage during NACRT was similar between the groups. Conclusions: MS placement compared to PS in patients receiving preoperative NACRT provided no significant benefits during the postoperative course of pancreatectomy. However, MS placement was associated with long stent patency while showing no economic disadvantage. Therefore, MS placement may be recommended in patients receiving preoperative NACRT for resectable pancreatic cancer.; 博士（医学）・乙第1467号・令和2年9月30日; © Société Internationale de Chirurgie 2018; This is a post-peer-review, pre-copyedit version of an article published in World journal of surgery. The final authenticated version is available online at: https://doi.org/10.1007/s00268-018-4820-6.; identifier:World journal of surgery Vol.43 No.2 p.642-648 (2019 Feb); identifier:03642313; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3783; identifier:World journal of surgery, 43(2): 642-648
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/1/01%e4%b9%991467%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/2/02%e4%b9%991467%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3783/3/03%e4%b9%991467%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s00268-018-4820-6
• Periodical Title (NCID): AA0089099X; https://ci.nii.ac.jp/ncid/AA0089099X
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU