The Prognosis and Recurrence Pattern of Right- and Left-Sided Colon Cancer in Stage II, Stage III, and Liver Metastasis After Curative Resection.

• 資料種別: 博士論文
• タイトル: The Prognosis and Recurrence Pattern of Right- and Left-Sided Colon Cancer in Stage II, Stage III, and Liver Metastasis After Curative Resection.
• 著者・編者: Nakamura, Yasuyuki; Hokuto, Daisuke; Koyama, Fumikazu; Matsuo, Yasuko; Nomi, Takeo; Yoshikawa, Takahiro; Kamitani, Naoki; Sadamitsu, Tomomi; Takei, Takeshi; Matsumoto, Yayoi; Iwasa, Yosuke; Fukuoka, Kohei; Obara, Shinsaku; Nakamoto, Takayuki; Kuge, Hiroyuki; Sho, Masayuki
• 著者標目: Nakamura, Yasuyuki; Hokuto, Daisuke; Koyama, Fumikazu; Matsuo, Yasuko; Nomi, Takeo; Yoshikawa, Takahiro; Kamitani, Naoki; Sadamitsu, Tomomi; Takei, Takeshi; Matsumoto, Yayoi; Iwasa, Yosuke; Fukuoka, Kohei; Obara, Shinsaku; Nakamoto, Takayuki; Kuge, Hiroyuki; Sho, Masayuki
• 出版事項: Korean Society of Coloproctology
• 出版年月日等: 2021-10
• 出版年（W3CDTF）: 2021-10
• 並列タイトル等: 根治切除後の結腸癌StageⅡ、StageⅢ、及び大腸癌肝転移における原発部位が与える影響
• タイトル（掲載誌）: Annals of coloproctology
• 巻号年月日等（掲載誌）: 37 5
• 掲載巻: 37
• 掲載号: 5
• 掲載ページ: 326-336
• ISSN（掲載誌）: ISSN : 2287-9714
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2021-03-15
• 報告番号: 乙第1495号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Right-sided colon cancer; Left-sided colon cancer; Colorectal liver metastasis
• 対象利用者: 一般
• 一般注記: type:Thesis; Purpose: Primary tumor location of colon cancer has been reported to affect the prognosis after curative resection. However, some reports suggested the impact was varied by tumor stage. This study analyzed the prognostic impact of the sidedness of colon cancer in stages II, III, and liver metastasis after curative resection using propensity-matched analysis. Methods: Right-sided colon cancer was defined as a tumor located from cecum to splenic flexure, while any more distal colon cancer was defined as left-sided colon cancer. Patients who underwent curative resection at Nara Medical University hospital between 2000 and 2016 were analyzed. Results: There were 110 patients with stage II, 100 patients with stage III, and 106 patients with liver metastasis. After propensity matching, 28 pairs with stage II and 32 pairs with stage III were identified. In the patients with stage II, overall survival (OS) and recurrence-free survival (RFS) were not significantly different for right- and left-sided colon cancers. In the patients with stage III, OS and RFS were significantly worse in right-sided colon cancer. In those with liver metastasis, OS of right-sided colon cancer was significantly worse than left-sided disease, while RFS was similar. Regarding metachronous liver metastasis, the difference was observed only in the patients whose primary colon cancer was stage III. In each stage, significantly higher rate of peritoneal recurrence was found in those with right-sided colon cancer. Conclusion: Sidedness of colon cancer had a significant and varied prognostic impact in patients with stage II, III, and liver metastasis after curative resection.; 博士（医学）・乙第1495号・令和3年3月15日; Copyright © 2021 The Korean Society of Coloproctology.; This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.; identifier:Annals of coloproctology Vol.37 No.5 p.326-336 (2021 Oct); identifier:22879714; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3919; identifier:Annals of coloproctology, 37(5): 326-336
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.3393/ac.2020.09.14
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/1/01%e4%b9%991495%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/2/02%e4%b9%991495%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/3/03%e4%b9%991495%e6%9c%ac%e6%96%87.pdf fulltext