The Prognosis and Recurrence Pattern of Right- and Left-Sided Colon Cancer in Stage II, Stage III, and Liver Metastasis After Curative Resection.

• Material Type: 博士論文
• Title: The Prognosis and Recurrence Pattern of Right- and Left-Sided Colon Cancer in Stage II, Stage III, and Liver Metastasis After Curative Resection.
• Author/Editor: Nakamura, Yasuyuki; Hokuto, Daisuke; Koyama, Fumikazu; Matsuo, Yasuko; Nomi, Takeo; Yoshikawa, Takahiro; Kamitani, Naoki; Sadamitsu, Tomomi; Takei, Takeshi; Matsumoto, Yayoi; Iwasa, Yosuke; Fukuoka, Kohei; Obara, Shinsaku; Nakamoto, Takayuki; Kuge, Hiroyuki; Sho, Masayuki
• Author Heading: Nakamura, Yasuyuki; Hokuto, Daisuke; Koyama, Fumikazu; Matsuo, Yasuko; Nomi, Takeo; Yoshikawa, Takahiro; Kamitani, Naoki; Sadamitsu, Tomomi; Takei, Takeshi; Matsumoto, Yayoi; Iwasa, Yosuke; Fukuoka, Kohei; Obara, Shinsaku; Nakamoto, Takayuki; Kuge, Hiroyuki; Sho, Masayuki
• Publication, Distribution, etc.: Korean Society of Coloproctology
• Publication Date: 2021-10
• Publication Date (W3CDTF): 2021-10
• Alternative Title: 根治切除後の結腸癌StageⅡ、StageⅢ、及び大腸癌肝転移における原発部位が与える影響
• Periodical title: Annals of coloproctology
• No. or year of volume/issue: 37 5
• Volume: 37
• Issue: 5
• Pages: 326-336
• ISSN (Periodical Title): ISSN : 2287-9714
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2021-03-15
• Dissertation Number: 乙第1495号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Right-sided colon cancer; Left-sided colon cancer; Colorectal liver metastasis
• Target Audience: 一般
• Note (General): type:Thesis; Purpose: Primary tumor location of colon cancer has been reported to affect the prognosis after curative resection. However, some reports suggested the impact was varied by tumor stage. This study analyzed the prognostic impact of the sidedness of colon cancer in stages II, III, and liver metastasis after curative resection using propensity-matched analysis. Methods: Right-sided colon cancer was defined as a tumor located from cecum to splenic flexure, while any more distal colon cancer was defined as left-sided colon cancer. Patients who underwent curative resection at Nara Medical University hospital between 2000 and 2016 were analyzed. Results: There were 110 patients with stage II, 100 patients with stage III, and 106 patients with liver metastasis. After propensity matching, 28 pairs with stage II and 32 pairs with stage III were identified. In the patients with stage II, overall survival (OS) and recurrence-free survival (RFS) were not significantly different for right- and left-sided colon cancers. In the patients with stage III, OS and RFS were significantly worse in right-sided colon cancer. In those with liver metastasis, OS of right-sided colon cancer was significantly worse than left-sided disease, while RFS was similar. Regarding metachronous liver metastasis, the difference was observed only in the patients whose primary colon cancer was stage III. In each stage, significantly higher rate of peritoneal recurrence was found in those with right-sided colon cancer. Conclusion: Sidedness of colon cancer had a significant and varied prognostic impact in patients with stage II, III, and liver metastasis after curative resection.; 博士（医学）・乙第1495号・令和3年3月15日; Copyright © 2021 The Korean Society of Coloproctology.; This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.; identifier:Annals of coloproctology Vol.37 No.5 p.326-336 (2021 Oct); identifier:22879714; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3919; identifier:Annals of coloproctology, 37(5): 326-336
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.3393/ac.2020.09.14
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

Table of Contents

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/1/01%e4%b9%991495%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/2/02%e4%b9%991495%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3919/3/03%e4%b9%991495%e6%9c%ac%e6%96%87.pdf fulltext