Retrospective analysis of heroin detoxification with buprenorphine in a psychiatric hospital in Japan.

• 資料種別: 博士論文
• タイトル: Retrospective analysis of heroin detoxification with buprenorphine in a psychiatric hospital in Japan.
• 著者・編者: Nagano, Tatsushi; Kimoto, Sohei; Aso, Katsuro; Komori, Takashi; Yamaguchi, Yasunari; Okamura, Kazuya; Yamamoto, Noriya; Kishimoto, Toshifumi
• 著者標目: Nagano, Tatsushi; Kimoto, Sohei; Aso, Katsuro; Komori, Takashi; Yamaguchi, Yasunari; Okamura, Kazuya; Yamamoto, Noriya; Kishimoto, Toshifumi
• 出版事項: Wiley
• 出版年月日等: 2020-12
• 出版年（W3CDTF）: 2020-12
• 並列タイトル等: 当院におけるヘロイン依存症者へのbuprenorphineによる解毒治療についての検討
• タイトル（掲載誌）: Neuropsychopharmacology reports
• 巻号年月日等（掲載誌）: 40 4
• 掲載巻: 40
• 掲載号: 4
• 掲載ページ: 376-382
• ISSN（掲載誌）: ISSN : 2574-173X
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2021-03-15
• 報告番号: 乙第1502号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: buprenorphine; Clinical Opiate Withdrawal Scale; detoxification; heroin; opioid use disorder
• 対象利用者: 一般
• 一般注記: type:Thesis; Aim: We assessed the efficacy of buprenorphine replacement taper therapy in a psychiatric hospital in Japan. Methods: Based on the medical records, a retrospective analysis was performed to evaluate the outcomes of buprenorphine replacement taper therapy in 106 subjects with heroin dependence. Results: We found that replacement and taper therapy with buprenorphine could significantly reduce withdrawal symptoms during detoxification. In addition, the completion rate of detoxification was significantly improved and the length of hospital stay was significantly reduced relative to those who received conventional treatment without buprenorphine. However, the readmission rate increased after the introduction of detoxication therapy with buprenorphine. Conclusion: The present findings suggest not only the efficacy and safety of buprenorphine replacement and taper therapy, but also the requirement for maintenance therapy for individuals with heroin dependence.; 博士（医学）・乙第1502号・令和3年3月15日; © 2020 The Authors. Neuropsycho pharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of NeuropsychoPharmacology. This is an open access article under the terms of the Creative Commons Attribution License(https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.; identifier:Neuropsychopharmacology reports Vol.40 No.4 p.376-382 (2020 Dec); identifier:2574173X; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3928; identifier:Neuropsychopharmacology reports, 40(4): 376-382
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1002/npr2.12147
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3928/1/01%e4%b9%991502%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3928/2/02%e4%b9%991502%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3928/3/03%e4%b9%991502%e6%9c%ac%e6%96%87.pdf fulltext