Retrospective analysis of heroin detoxification with buprenorphine in a psychiatric hospital in Japan.

• Material Type: 博士論文
• Title: Retrospective analysis of heroin detoxification with buprenorphine in a psychiatric hospital in Japan.
• Author/Editor: Nagano, Tatsushi; Kimoto, Sohei; Aso, Katsuro; Komori, Takashi; Yamaguchi, Yasunari; Okamura, Kazuya; Yamamoto, Noriya; Kishimoto, Toshifumi
• Author Heading: Nagano, Tatsushi; Kimoto, Sohei; Aso, Katsuro; Komori, Takashi; Yamaguchi, Yasunari; Okamura, Kazuya; Yamamoto, Noriya; Kishimoto, Toshifumi
• Publication, Distribution, etc.: Wiley
• Publication Date: 2020-12
• Publication Date (W3CDTF): 2020-12
• Alternative Title: 当院におけるヘロイン依存症者へのbuprenorphineによる解毒治療についての検討
• Periodical title: Neuropsychopharmacology reports
• No. or year of volume/issue: 40 4
• Volume: 40
• Issue: 4
• Pages: 376-382
• ISSN (Periodical Title): ISSN : 2574-173X
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2021-03-15
• Dissertation Number: 乙第1502号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: buprenorphine; Clinical Opiate Withdrawal Scale; detoxification; heroin; opioid use disorder
• Target Audience: 一般
• Note (General): type:Thesis; Aim: We assessed the efficacy of buprenorphine replacement taper therapy in a psychiatric hospital in Japan. Methods: Based on the medical records, a retrospective analysis was performed to evaluate the outcomes of buprenorphine replacement taper therapy in 106 subjects with heroin dependence. Results: We found that replacement and taper therapy with buprenorphine could significantly reduce withdrawal symptoms during detoxification. In addition, the completion rate of detoxification was significantly improved and the length of hospital stay was significantly reduced relative to those who received conventional treatment without buprenorphine. However, the readmission rate increased after the introduction of detoxication therapy with buprenorphine. Conclusion: The present findings suggest not only the efficacy and safety of buprenorphine replacement and taper therapy, but also the requirement for maintenance therapy for individuals with heroin dependence.; 博士（医学）・乙第1502号・令和3年3月15日; © 2020 The Authors. Neuropsycho pharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of NeuropsychoPharmacology. This is an open access article under the terms of the Creative Commons Attribution License(https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.; identifier:Neuropsychopharmacology reports Vol.40 No.4 p.376-382 (2020 Dec); identifier:2574173X; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3928; identifier:Neuropsychopharmacology reports, 40(4): 376-382
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1002/npr2.12147
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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