Long-term prognosis of patients undergoing radiofrequency catheter ablation for atrial fibrillation: comparison between heart failure subtypes based on left ventricular ejection fraction.

• 資料種別: 博士論文
• タイトル: Long-term prognosis of patients undergoing radiofrequency catheter ablation for atrial fibrillation: comparison between heart failure subtypes based on left ventricular ejection fraction.
• 著者・編者: Fujimoto, Hajime; Doi, Naofumi; Okayama, Satoshi; Naito, Masaki; Kobori, Atsushi; Kaitani, Kazuaki; Inoue, Koichi; Kurotobi, Toshiya; Morishima, Itsuro; Yamaji, Hirosuke; Matsui, Yumie; Nakazawa, Yuko; Kusano, Kengo; Hirai, Kaeko; Nakai, Takehito; Suzuki, Megumi; Yano, Hiroki; Sakai, Satoshi; Kimura, Takeshi; Shizuta, Satoshi; Saito, Yoshihiko
• 著者標目: Fujimoto, Hajime; Doi, Naofumi; Okayama, Satoshi; Naito, Masaki; Kobori, Atsushi; Kaitani, Kazuaki; Inoue, Koichi; Kurotobi, Toshiya; Morishima, Itsuro; Yamaji, Hirosuke; Matsui, Yumie; Nakazawa, Yuko; Kusano, Kengo; Hirai, Kaeko; Nakai, Takehito; Suzuki, Megumi; Yano, Hiroki; Sakai, Satoshi; Kimura, Takeshi; Shizuta, Satoshi; Saito, Yoshihiko
• 出版事項: Oxford University Press
• 出版年月日等: 2021-08-31
• 出版年（W3CDTF）: 2021-08-31
• 並列タイトル等: 心不全を合併した心房細動患者のカテーテルアブレーション後の長期予後 : 左室駆出率に基づいた心不全のサブタイプ間における比較
• タイトル（掲載誌）: Europace
• 巻号年月日等（掲載誌）: 24 4
• 掲載巻: 24
• 掲載号: 4
• ISSN（掲載誌）: ISSN : 1099-5129
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2021-12-21
• 報告番号: 甲第802号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Atrial fibrillation; Catheter ablation; Heart failure; Ejection fraction
• 対象利用者: 一般
• 一般注記: type:Thesis; Aims: Heart failure (HF) prognosis has been reported similar in patients with preserved vs. reduced left ventricular ejection fraction (LVEF). This study compared the long-term prognosis of HF patients undergoing radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). Methods and results: Among 5010 patients undergoing RFCA in Kansai Plus AF registry, 656 patients (13.1%) with a documented history of HF were enrolled in the study before RFCA. The primary endpoint was a composite of all-cause death, HF hospitalization, and stroke or systemic embolism. Patients with reduced (<40%), mid-range (40-49%), and preserved (≥50%) LVEF were 98 (14.9%), 107 (16.3%), and 451 (68.8%) patients, respectively. The prevalence of ischaemic heart disease and cardiomyopathies was higher among patients with reduced as compared with preserved LVEF (27.6% vs. 10.0%, P < 0.05 and 36.7% vs. 15.3%, P < 0.05, respectively). The median follow-up period was 2.9 years. The 3-year cumulative risk for the primary endpoint was higher in patients with reduced LVEF (32.7%) compared to those with mid-range (11.7%) or preserved (11.6%) LVEF (P < 0.001). Reduced LVEF was the most significant independent risk factor for primary endpoint (hazard ratio, 2.83; 95% confidence interval 1.74-4.61, P < 0.001). The 3-year arrhythmia recurrence rate was similar among the groups (48.2%, 42.8%, and 47.3%, respectively, P = 0.75). Conclusion : This study raises hypothesis that patients with HFrEF and AF had approximately three times higher risk for a composite of all-cause death, HF hospitalization, and stroke or systemic embolism after AF ablation compared with patients with HFmrEF or HFpEF.; 博士（医学）・甲第802号・令和3年12月21日; Copyright: © Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2021.; This is a pre-copyedited, author-produced version of an article accepted for publication in Europace following peer review. The version of record "Europace Online ahead of print (2021 Aug 31;euab201) is available online at: https://doi.org/10.1093/europace/euab201.; identifier:Europace Vol.24 No.4 p.576-586 (2022 Apr); identifier:10995129; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3951; identifier:Europace, 24(4)
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1093/europace/euab201
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/1/01%e7%94%b2802%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/2/02%e7%94%b2802%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/6/03%e7%94%b2802%e6%9c%ac%e6%96%87.pdf fulltext