Long-term prognosis of patients undergoing radiofrequency catheter ablation for atrial fibrillation: comparison between heart failure subtypes based on left ventricular ejection fraction.

• Material Type: 博士論文
• Title: Long-term prognosis of patients undergoing radiofrequency catheter ablation for atrial fibrillation: comparison between heart failure subtypes based on left ventricular ejection fraction.
• Author/Editor: Fujimoto, Hajime; Doi, Naofumi; Okayama, Satoshi; Naito, Masaki; Kobori, Atsushi; Kaitani, Kazuaki; Inoue, Koichi; Kurotobi, Toshiya; Morishima, Itsuro; Yamaji, Hirosuke; Matsui, Yumie; Nakazawa, Yuko; Kusano, Kengo; Hirai, Kaeko; Nakai, Takehito; Suzuki, Megumi; Yano, Hiroki; Sakai, Satoshi; Kimura, Takeshi; Shizuta, Satoshi; Saito, Yoshihiko
• Author Heading: Fujimoto, Hajime; Doi, Naofumi; Okayama, Satoshi; Naito, Masaki; Kobori, Atsushi; Kaitani, Kazuaki; Inoue, Koichi; Kurotobi, Toshiya; Morishima, Itsuro; Yamaji, Hirosuke; Matsui, Yumie; Nakazawa, Yuko; Kusano, Kengo; Hirai, Kaeko; Nakai, Takehito; Suzuki, Megumi; Yano, Hiroki; Sakai, Satoshi; Kimura, Takeshi; Shizuta, Satoshi; Saito, Yoshihiko
• Publication, Distribution, etc.: Oxford University Press
• Publication Date: 2021-08-31
• Publication Date (W3CDTF): 2021-08-31
• Alternative Title: 心不全を合併した心房細動患者のカテーテルアブレーション後の長期予後 : 左室駆出率に基づいた心不全のサブタイプ間における比較
• Periodical title: Europace
• No. or year of volume/issue: 24 4
• Volume: 24
• Issue: 4
• ISSN (Periodical Title): ISSN : 1099-5129
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2021-12-21
• Dissertation Number: 甲第802号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Atrial fibrillation; Catheter ablation; Heart failure; Ejection fraction
• Target Audience: 一般
• Note (General): type:Thesis; Aims: Heart failure (HF) prognosis has been reported similar in patients with preserved vs. reduced left ventricular ejection fraction (LVEF). This study compared the long-term prognosis of HF patients undergoing radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). Methods and results: Among 5010 patients undergoing RFCA in Kansai Plus AF registry, 656 patients (13.1%) with a documented history of HF were enrolled in the study before RFCA. The primary endpoint was a composite of all-cause death, HF hospitalization, and stroke or systemic embolism. Patients with reduced (<40%), mid-range (40-49%), and preserved (≥50%) LVEF were 98 (14.9%), 107 (16.3%), and 451 (68.8%) patients, respectively. The prevalence of ischaemic heart disease and cardiomyopathies was higher among patients with reduced as compared with preserved LVEF (27.6% vs. 10.0%, P < 0.05 and 36.7% vs. 15.3%, P < 0.05, respectively). The median follow-up period was 2.9 years. The 3-year cumulative risk for the primary endpoint was higher in patients with reduced LVEF (32.7%) compared to those with mid-range (11.7%) or preserved (11.6%) LVEF (P < 0.001). Reduced LVEF was the most significant independent risk factor for primary endpoint (hazard ratio, 2.83; 95% confidence interval 1.74-4.61, P < 0.001). The 3-year arrhythmia recurrence rate was similar among the groups (48.2%, 42.8%, and 47.3%, respectively, P = 0.75). Conclusion : This study raises hypothesis that patients with HFrEF and AF had approximately three times higher risk for a composite of all-cause death, HF hospitalization, and stroke or systemic embolism after AF ablation compared with patients with HFmrEF or HFpEF.; 博士（医学）・甲第802号・令和3年12月21日; Copyright: © Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2021.; This is a pre-copyedited, author-produced version of an article accepted for publication in Europace following peer review. The version of record "Europace Online ahead of print (2021 Aug 31;euab201) is available online at: https://doi.org/10.1093/europace/euab201.; identifier:Europace Vol.24 No.4 p.576-586 (2022 Apr); identifier:10995129; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3951; identifier:Europace, 24(4)
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/1/01%e7%94%b2802%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/2/02%e7%94%b2802%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3951/6/03%e7%94%b2802%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1093/europace/euab201
• Periodical Title (NCID): AA11696999; https://ci.nii.ac.jp/ncid/AA11696999
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU