Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect

• 資料種別: 博士論文
• タイトル: Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect
• 著者・編者: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• 著者標目: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• 出版事項: MDPI
• 出版年月日等: 2022-08-31
• 出版年（W3CDTF）: 2022
• 並列タイトル等: 心室中隔欠損症に対する小児心臓カテーテル検査における麻酔方法と重症合併症の関連
• タイトル（掲載誌）: Journal of clinical medicine
• 巻号年月日等（掲載誌）: 11 17
• 掲載巻: 11
• 掲載号: 17
• 掲載ページ: Article No.5165-
• ISSN（掲載誌）: ISSN : 2077-0383
• 授与機関名: 奈良県立医科大学
• 報告番号: 甲第867号
• 学位: 博士（医学）
• 件名標目: cardiac catheterization; anesthesia; ventricular septal defect
• 対象利用者: 一般
• 一般注記: 出版タイプ： VoR; type:Thesis; Pediatric cardiac catheterization requires unconsciousness and immobilization through general anesthesia or sedation. This study aimed to compare the occurrence of severe complications in pediatric diagnostic cardiac catheterization for ventricular septal defect between general anesthesia and sedation performed under similar institutional environments. Using the Japanese Diagnosis Procedure Combination database, we retrospectively identified pediatric patients (aged <2 years) who underwent diagnostic cardiac catheterization for ventricular septal defect between July 2010 and March 2019. The composite outcome was the occurrence of severe complications, including catecholamine use and intensive care unit admission, within seven days after catheterization. Overlap weighting based on propensity scores was used to adjust for patient- and hospital-level confounding factors. We identified 3159 patients from 87 hospitals, including 930 under general anesthesia and 2229 under sedation. The patient- and hospital-level baseline characteristics differed between the groups. After adjustment, the proportion of patients with severe complications was significantly higher in the general anesthesia group than in the sedation group (2.4% vs. 0.6%; risk difference, 1.8% [95% confidence interval, 0.93–2.6%]). Severe complications occurred more frequently in the general anesthesia group than in the sedation group. Further research on anesthetic methods is necessary to assess the safety and accuracy of pediatric diagnostic cardiac catheterization.; 博士（医学）・甲第867号・令和5年3月15日; © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; identifier:Journal of clinical medicine Vol.11 No.17 Article No.5165 (2022 Aug); identifier:20770383; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4099; identifier:Journal of clinical medicine, 11(17): Article No.5165
• 一次資料へのリンクURL: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/1/01%e7%94%b2867%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/2/02%e7%94%b2867%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/6/03%e7%94%b2867%e6%9c%ac%e6%96%87.pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.3390/ jcm11175165; https://doi.org/10.3390/ jcm11175165
• 関連情報（NCID）: BC08567618; https://ci.nii.ac.jp/ncid/BC08567618
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU