Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect

• Material Type: 博士論文
• Title: Severe Complications after General Anesthesia versus Sedation during Pediatric Diagnostic Cardiac Catheterization for Ventricular Septal Defect
• Author/Editor: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• Author Heading: Ogawa, Yuki; Yamana, Hayato; Noda, Tatsuya; Kishimoto, Miwa; Yoshihara, Shingo; Kanaoka, Koshiro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Kawaraguchi, Masahiko; Imamura, Tomoaki
• Publication, Distribution, etc.: MDPI
• Publication Date: 2022-08-31
• Publication Date (W3CDTF): 2022-08-31
• Alternative Title: 心室中隔欠損症に対する小児心臓カテーテル検査における麻酔方法と重症合併症の関連
• Periodical title: Journal of clinical medicine
• No. or year of volume/issue: 11 17
• Volume: 11
• Issue: 17
• Pages: Article No.5165-
• ISSN (Periodical Title): ISSN : 2077-0383
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2023-03-15
• Dissertation Number: 甲第867号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: cardiac catheterization; anesthesia; ventricular septal defect
• Target Audience: 一般
• Note (General): type:Thesis; Pediatric cardiac catheterization requires unconsciousness and immobilization through general anesthesia or sedation. This study aimed to compare the occurrence of severe complications in pediatric diagnostic cardiac catheterization for ventricular septal defect between general anesthesia and sedation performed under similar institutional environments. Using the Japanese Diagnosis Procedure Combination database, we retrospectively identified pediatric patients (aged <2 years) who underwent diagnostic cardiac catheterization for ventricular septal defect between July 2010 and March 2019. The composite outcome was the occurrence of severe complications, including catecholamine use and intensive care unit admission, within seven days after catheterization. Overlap weighting based on propensity scores was used to adjust for patient- and hospital-level confounding factors. We identified 3159 patients from 87 hospitals, including 930 under general anesthesia and 2229 under sedation. The patient- and hospital-level baseline characteristics differed between the groups. After adjustment, the proportion of patients with severe complications was significantly higher in the general anesthesia group than in the sedation group (2.4% vs. 0.6%; risk difference, 1.8% [95% confidence interval, 0.93–2.6%]). Severe complications occurred more frequently in the general anesthesia group than in the sedation group. Further research on anesthetic methods is necessary to assess the safety and accuracy of pediatric diagnostic cardiac catheterization.; 博士（医学）・甲第867号・令和5年3月15日; © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; identifier:Journal of clinical medicine Vol.11 No.17 Article No.5165 (2022 Aug); identifier:20770383; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4099; identifier:Journal of clinical medicine, 11(17): Article No.5165
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.3390/ jcm11175165
• Related Material (NCID): BC08567618; https://ci.nii.ac.jp/ncid/BC08567618
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

Table of Contents

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/1/01%e7%94%b2867%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/2/02%e7%94%b2867%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4099/6/03%e7%94%b2867%e6%9c%ac%e6%96%87.pdf fulltext