Factors associated with the increased risk of atlantoaxial osteoarthritis: a retrospective study

• 資料種別: 博士論文
• タイトル: Factors associated with the increased risk of atlantoaxial osteoarthritis: a retrospective study
• 著者・編者: Suga, Yuma; Shigematsu, Hideki; Tanaka, Masato; Okuda, Akinori; Kawasaki, Sachiko; Yamamoto, Yusuke; Ikejiri, Masaki; Asai, Hideki; Fukushima, Hidetada; Tanaka, Yasuhito
• 著者標目: Suga, Yuma; Shigematsu, Hideki; Tanaka, Masato; Okuda, Akinori; Kawasaki, Sachiko; Yamamoto, Yusuke; Ikejiri, Masaki; Asai, Hideki; Fukushima, Hidetada; Tanaka, Yasuhito
• 出版事項: Springer
• 出版年月日等: 2022-12
• 出版年（W3CDTF）: 2022-12
• 並列タイトル等: 外側環軸関節の関節症性変化のリスク増加に関連する要因; 後ろ向き研究
• タイトル（掲載誌）: European spine journal
• 巻号年月日等（掲載誌）: 31 12
• 掲載巻: 31
• 掲載号: 12
• 掲載ページ: 3418-3425
• ISSN（掲載誌）: ISSN : 0940-6719
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2023-03-15
• 報告番号: 甲第873号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Neck pain; Suboccipital headaches; Atlantoaxial osteoarthritis; Atlantodens joint; Calcification; Transverse ligament
• 対象利用者: 一般
• 一般注記: type:Thesis; Purpose Atlantodens osteoarthritis and atlantoaxial osteoarthritis cause neck pain and suboccipital headaches. Currently, knowledge on the risk factors for atlantoaxial osteoarthritis is lacking. This study aimed to investigate the factors related to the increased risk of atlantoaxial osteoarthritis. Methods We analyzed computed tomography (CT) images of the upper cervical spine of 1266 adult trauma patients for whom upper cervical spine CT was performed at our hospital between 2014 and 2019. The degree of atlantoaxial osteoarthritis was quantified as none-to-mild (not having osteoarthritis) or moderateto- severe (having osteoarthritis). Risk factors associated with atlantoaxial osteoarthritis were identified using univariate and multivariable logistic regression analyses. Results The study group included 69.4% men, and the overall average age of the study population was 54.9 ± 20.4 years. The following factors were independently and significantly associated with atlantoaxial osteoarthritis in the multivariable logistic regression analysis: age in the sixth decade or older (odds ratio [OR], 20.5; 95% confidence interval [CI], 6.2‒67.2, p < 0.001), having calcific synovitis (OR, 4.9; 95% CI, 2.4‒9.9, p < 0.001), women sex (OR, 3.3; 95% CI, 1.9‒5.7, p = 0.002), and not having atlantodens osteoarthritis (OR, 2.1; 95% CI, 1.2‒3.8, p = 0.014). Conclusion In the multivariable logistic regression analysis, age in the sixth decade or older, calcification of the transverse ligament, being women, and not having atlantodens osteoarthritis were found to be significantly associated with atlantoaxial osteoarthritis. Delayed diagnosis and treatment can be avoided by focusing on these risk factors.; 博士（医学）・甲第873号・令和5年3月15日; This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00586-022-07414-5; identifier:European spine journal Vol.31 No.12 p.3418-3425 (2022 Dec); identifier:09406719; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4105; identifier:European spine journal, 31(12): 3418-3425
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1007/s00586-022-07414-5
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/1/01%e7%94%b2873%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/2/02%e7%94%b2873%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/6/03%e7%94%b2873%e6%9c%ac%e6%96%87.pdf fulltext