Factors associated with the increased risk of atlantoaxial osteoarthritis: a retrospective study

• Material Type: 博士論文
• Title: Factors associated with the increased risk of atlantoaxial osteoarthritis: a retrospective study
• Author/Editor: Suga, Yuma; Shigematsu, Hideki; Tanaka, Masato; Okuda, Akinori; Kawasaki, Sachiko; Yamamoto, Yusuke; Ikejiri, Masaki; Asai, Hideki; Fukushima, Hidetada; Tanaka, Yasuhito
• Author Heading: Suga, Yuma; Shigematsu, Hideki; Tanaka, Masato; Okuda, Akinori; Kawasaki, Sachiko; Yamamoto, Yusuke; Ikejiri, Masaki; Asai, Hideki; Fukushima, Hidetada; Tanaka, Yasuhito
• Publication, Distribution, etc.: Springer
• Publication Date: 2022-12
• Publication Date (W3CDTF): 2022-12
• Alternative Title: 外側環軸関節の関節症性変化のリスク増加に関連する要因; 後ろ向き研究
• Periodical title: European spine journal
• No. or year of volume/issue: 31 12
• Volume: 31
• Issue: 12
• Pages: 3418-3425
• ISSN (Periodical Title): ISSN : 0940-6719
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2023-03-15
• Dissertation Number: 甲第873号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Neck pain; Suboccipital headaches; Atlantoaxial osteoarthritis; Atlantodens joint; Calcification; Transverse ligament
• Target Audience: 一般
• Note (General): type:Thesis; Purpose Atlantodens osteoarthritis and atlantoaxial osteoarthritis cause neck pain and suboccipital headaches. Currently, knowledge on the risk factors for atlantoaxial osteoarthritis is lacking. This study aimed to investigate the factors related to the increased risk of atlantoaxial osteoarthritis. Methods We analyzed computed tomography (CT) images of the upper cervical spine of 1266 adult trauma patients for whom upper cervical spine CT was performed at our hospital between 2014 and 2019. The degree of atlantoaxial osteoarthritis was quantified as none-to-mild (not having osteoarthritis) or moderateto- severe (having osteoarthritis). Risk factors associated with atlantoaxial osteoarthritis were identified using univariate and multivariable logistic regression analyses. Results The study group included 69.4% men, and the overall average age of the study population was 54.9 ± 20.4 years. The following factors were independently and significantly associated with atlantoaxial osteoarthritis in the multivariable logistic regression analysis: age in the sixth decade or older (odds ratio [OR], 20.5; 95% confidence interval [CI], 6.2‒67.2, p < 0.001), having calcific synovitis (OR, 4.9; 95% CI, 2.4‒9.9, p < 0.001), women sex (OR, 3.3; 95% CI, 1.9‒5.7, p = 0.002), and not having atlantodens osteoarthritis (OR, 2.1; 95% CI, 1.2‒3.8, p = 0.014). Conclusion In the multivariable logistic regression analysis, age in the sixth decade or older, calcification of the transverse ligament, being women, and not having atlantodens osteoarthritis were found to be significantly associated with atlantoaxial osteoarthritis. Delayed diagnosis and treatment can be avoided by focusing on these risk factors.; 博士（医学）・甲第873号・令和5年3月15日; This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00586-022-07414-5; identifier:European spine journal Vol.31 No.12 p.3418-3425 (2022 Dec); identifier:09406719; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4105; identifier:European spine journal, 31(12): 3418-3425
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/1/01%e7%94%b2873%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/2/02%e7%94%b2873%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4105/6/03%e7%94%b2873%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s00586-022-07414-5
• Periodical Title (NCID): AA10852035; https://ci.nii.ac.jp/ncid/AA10852035
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU