Hepatocyte Growth Factor

• 資料種別: 図書
• タイトル: Hepatocyte Growth Factor
• 著者・編者: Sakai, Katsuya; Kinoshita, Takayoshi; Matsumoto, Kunio; 酒井, 克也; 松本, 邦夫
• 著者標目: Sakai, Katsuya; Kinoshita, Takayoshi; Matsumoto, Kunio; 酒井, 克也; 松本, 邦夫
• 出版事項: Elsevier
• 出版年月日等: 2014-12-15
• 出版年（W3CDTF）: 2014-12-15
• タイトル（掲載誌）: Reference Module in Biomedical Research
• 本文の言語コード: eng
• 件名標目: Amyotrophic lateral sclerosis; Cancer stem cell; Drug resistance; Epithelial-mesenchymal interaction; Growth factor; Hepatocyte growth factor; Liver regeneration; Met; Metastasis; Molecular targeted drug; Morphogenesis; Receptor tyrosine kinase; Tissue regeneration
• 対象利用者: 一般
• 一般注記: 金沢大学がん進展制御研究所; Hepatocyte growth factor (HGF) exerts biological activity through the Met receptor tyrosine kinase. HGF plays essential roles in the embryonic development of the liver and placenta, and in the migration of myogenic precursor cells. In mature tissues, HGF plays roles in tissue protection and regeneration, including in the liver and kidney. HGF participates in invasion, metastasis, and drug resistance. Drug development targeting HGF-Met has been challenging. One focus has been the use of recombinant HGF as a biological drug and another has been the use of HGF-Met inhibitors for cancer treatment. Clinical trials using HGF or HGF-Met inhibitors are ongoing. © 2014 Elsevier Inc. All rights reserved.; [Book Chapter]
• DOI: 10.24517/00027504
• オンライン閲覧公開範囲: 限定公開
• 関連情報（DOI）: 10.1016/B978-0-12-801238-3.04055-1
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 金沢大学 : 金沢大学学術情報リポジトリKURA