Hepatocyte Growth Factor

Material type: 図書

Author: Sakai, Katsuyaほか

Publisher: Elsevier

Publication date: 2014-12-15

Material Format: Digital

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Note (General)：: 金沢大学がん進展制御研究所Hepatocyte growth factor (HGF) exerts biological activity through the Met receptor tyrosine kinase. HGF plays essential roles in the embr...

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Material Type: 図書
Title: Hepatocyte Growth Factor
Author/Editor: Sakai, Katsuya
Kinoshita, Takayoshi
Matsumoto, Kunio
酒井, 克也
松本, 邦夫
Author Heading: Sakai, Katsuya
Kinoshita, Takayoshi
Matsumoto, Kunio
酒井, 克也
松本, 邦夫
Publication, Distribution, etc.: Elsevier
Publication Date: 2014-12-15
Publication Date (W3CDTF): 2014-12-15
Periodical title: Reference Module in Biomedical Research
Text Language Code: eng
Subject Heading: Amyotrophic lateral sclerosis
Cancer stem cell
Drug resistance
Epithelial-mesenchymal interaction
Growth factor
Hepatocyte growth factor
Liver regeneration
Met
Metastasis
Molecular targeted drug
Morphogenesis
Receptor tyrosine kinase
Tissue regeneration
Target Audience: 一般
Note (General): 金沢大学がん進展制御研究所
Hepatocyte growth factor (HGF) exerts biological activity through the Met receptor tyrosine kinase. HGF plays essential roles in the embryonic development of the liver and placenta, and in the migration of myogenic precursor cells. In mature tissues, HGF plays roles in tissue protection and regeneration, including in the liver and kidney. HGF participates in invasion, metastasis, and drug resistance. Drug development targeting HGF-Met has been challenging. One focus has been the use of recombinant HGF as a biological drug and another has been the use of HGF-Met inhibitors for cancer treatment. Clinical trials using HGF or HGF-Met inhibitors are ongoing. © 2014 Elsevier Inc. All rights reserved.
[Book Chapter]
DOI: 10.24517/00027504
Source: https://kanazawa-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=27517&item_no=1&attribute_id=26&file_no=1
https://kanazawa-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=27517&item_no=1&attribute_id=26&file_no=1
Access Restrictions: 限定公開
Rights (production): CC BY-NC-ND
Related Material (DOI): 10.1016/B978-0-12-801238-3.04055-1
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 金沢大学 : 金沢大学学術情報リポジトリKURA