Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model

• 資料種別: 博士論文
• タイトル: Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model
• 著者・編者: Takaya, Tatsuo; Hiroaki, Mimura; Matsuda, Saeka; Nakano, Keisuke; Tsujigiwa, Hidetsugu; Tomida, Mihoko; Okafuji, Norimasa; Fujii, Takeo; Kawakami, Toshiyuki; 髙谷, 達夫
• 出版年月日等: 2016-02-05
• 出版年（W3CDTF）: 2016-02-05
• 並列タイトル等: 実験的咬合性外傷による歯根膜の細胞動態
• 授与機関名: 松本歯科大学
• 授与年月日: 2016-02-05
• 授与年月日（W3CDTF）: 2016-02-05
• 報告番号: 甲第174号
• 学位: 博士（歯学）
• 博論授与番号: 甲第174号
• 本文の言語コード: eng
• 件名標目: Occlusal trauma; Periodontal tissue; Green fluorescent protein(GFP); Ki67; Mouse
• 一般注記: Using a model of experimental occlusal trauma in mice, we investigated cytological kinetics of periodontal ligament by means of histopathological, immunohistochemical, and photographical analysis methods. At furcation areas of molar teeth in the experimental group on day 4, the increase of cells in periodontal ligament was seen. The cells with a round-shaped nucleus were deeply stained in the hematoxylin-eosin. Ki67 positive nuclei showed a prominent increase in the experimental groups on days 4 and 7. Green Fluorescent Protein (GFP) positivity also revealed cell movement, but this action was slightly slow compared to Ki67 staining specimens. It was indicated that the homeostasis is mechanism of periodontal ligament receiving the excessive occlusal loading was promoted by osteoclasts and macrophages from bone-marrow-derived cells migrated to the periodontal ligament. The remodeling of periodontal ligament with the acceleration of cell growth was evoked from the experiment for the group on day 4 and after day 7. The findings suggested that periodontal ligament at furcation areas of molar teeth in occlusal trauma model was recovered by using both of the cells in situ and the bone-marrow-derived cells.; 2015; identifier:甲第174号
• 国立国会図書館永続的識別子: info:ndljp/pid/10164519; https://dl.ndl.go.jp/pid/10164519
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2016-08-02T06:56:17+09:00
• 作成日（W3CDTF）: 2016-06-02
• 記録形式（IMT）: PDF
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 原資料（URI）: http://www.medsci.org/v12p0544.htm; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502058/
• 関連情報: 投稿雑誌：Takaya, T. et al. Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model. International Journal of Medical Sciences. 2015; 12(7): 544-551. © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
• 掲載誌（URI）: http://id.nii.ac.jp/1070/00002495/
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp