Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model

• Material Type: 博士論文
• Title: Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model
• Author/Editor: Takaya, Tatsuo; Hiroaki, Mimura; Matsuda, Saeka; Nakano, Keisuke; Tsujigiwa, Hidetsugu; Tomida, Mihoko; Okafuji, Norimasa; Fujii, Takeo; Kawakami, Toshiyuki; 髙谷, 達夫
• Publication Date: 2016-02-05
• Publication Date (W3CDTF): 2016-02-05
• Alternative Title: 実験的咬合性外傷による歯根膜の細胞動態
• Degree grantor/type: 松本歯科大学
• Date Granted: 2016-02-05
• Date Granted (W3CDTF): 2016-02-05
• Dissertation Number: 甲第174号
• Degree Type: 博士（歯学）
• Conferring No. (Dissertation): 甲第174号
• Text Language Code: eng
• Subject Heading: Occlusal trauma; Periodontal tissue; Green fluorescent protein(GFP); Ki67; Mouse
• Note (General): Using a model of experimental occlusal trauma in mice, we investigated cytological kinetics of periodontal ligament by means of histopathological, immunohistochemical, and photographical analysis methods. At furcation areas of molar teeth in the experimental group on day 4, the increase of cells in periodontal ligament was seen. The cells with a round-shaped nucleus were deeply stained in the hematoxylin-eosin. Ki67 positive nuclei showed a prominent increase in the experimental groups on days 4 and 7. Green Fluorescent Protein (GFP) positivity also revealed cell movement, but this action was slightly slow compared to Ki67 staining specimens. It was indicated that the homeostasis is mechanism of periodontal ligament receiving the excessive occlusal loading was promoted by osteoclasts and macrophages from bone-marrow-derived cells migrated to the periodontal ligament. The remodeling of periodontal ligament with the acceleration of cell growth was evoked from the experiment for the group on day 4 and after day 7. The findings suggested that periodontal ligament at furcation areas of molar teeth in occlusal trauma model was recovered by using both of the cells in situ and the bone-marrow-derived cells.; 2015; identifier:甲第174号
• Persistent ID (NDL): info:ndljp/pid/10164519; https://dl.ndl.go.jp/pid/10164519
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• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2016-08-02T06:56:17+09:00
• Date Created (W3CDTF): 2016-06-02
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
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• Original Material (URI): http://www.medsci.org/v12p0544.htm; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502058/
• Related Material: 投稿雑誌：Takaya, T. et al. Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model. International Journal of Medical Sciences. 2015; 12(7): 544-551. © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
• Periodical Title (URI): http://id.nii.ac.jp/1070/00002495/
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp