Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.

• 資料種別: 博士論文
• タイトル: Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.
• 著者・編者: Maruyama, Katsuya
• 出版事項: 新潟大学
• 出版年月日等: 2017-03-23
• 出版年（W3CDTF）: 2017-03-23
• 並列タイトル等: Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.; 前立腺癌に対する重粒子線治療後5年間のQOL評価
• 授与機関名: 新潟大学
• 授与年月日: 2017-03-23
• 授与年月日（W3CDTF）: 2017-03-23
• 報告番号: 甲第4242号
• 学位: 博士（医学）
• 博論授与番号: 甲第4242号
• 本文の言語コード: eng
• 件名標目: prostate cancer; carbon ion radiotherapy; quality of life; prospective study
• 一般注記: The aim of this study was to prospectively assess 5-year health-related quality of life (HRQOL) of patients treated with carbon ion radiotherapy (C-ion RT) for clinically localized prostate cancer. A total of 417 patients received carbon ion radiotherapy at a total dose of 63-66 Gray-equivalents (GyE) in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy (ADT) were administered for intermediate and high-risk patients. A HRQOL assessment was performed at five time points (immediately before the initiation of C-ion RT, immediately after, and at 12, 36 and 60 months after completion of C-ion RT) using Functional Assessment of Cancer Therapy (FACT) questionnaires. FACT-G and FACT-P scores were significantly decreased; however, the absolute change after 60 months was minimal. The transient decreases in the Trial Outcome Index (TOI) score returned to their baseline levels. Use of ADT, presence of adverse events, and biochemical failure were related to lower scores. Scores of subdomains of FACT instruments indicated characteristic changes. The pattern of HRQOL change after C-ion RT was similar to that of other modalities. Further controlled studies focusing on a HRQOL in patients with prostate cancer are warranted.; 学位の種類: 博士（医学）. 報告番号: 甲第4242号. 学位記番号: 新大院博（医）甲第720号. 学位授与年月日: 平成29年3月23日; The Journal of Radiation Research 58(2)260-266,2017; 新大院博（医）甲第720号
• DOI: info:doi/10.1093/jrr/rrw122; https://doi.org/info:doi/10.1093/jrr/rrw122
• 国立国会図書館永続的識別子: info:ndljp/pid/10371254; https://dl.ndl.go.jp/pid/10371254
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2017-07-03T04:10:06+09:00
• 作成日（W3CDTF）: 2019-08-05
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10191/47573
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp