Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.
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- Material Type
- 博士論文
- Author/Editor
- Maruyama, Katsuya
- Publication, Distribution, etc.
- Publication Date
- 2017-03-23
- Publication Date (W3CDTF)
- 2017-03-23
- Alternative Title
- Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.前立腺癌に対する重粒子線治療後5年間のQOL評価
- Degree Grantor
- 新潟大学
- Date Granted
- 2017-03-23
- Date Granted (W3CDTF)
- 2017-03-23
- Dissertation Number
- 甲第4242号
- Degree Type
- 博士（医学）
- Conferring No. (Dissertation)
- 甲第4242号
- Text Language Code
- eng
- Note (General)
- The aim of this study was to prospectively assess 5-year health-related quality of life (HRQOL) of patients treated with carbon ion radiotherapy (C-ion RT) for clinically localized prostate cancer. A total of 417 patients received carbon ion radiotherapy at a total dose of 63-66 Gray-equivalents (GyE) in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy (ADT) were administered for intermediate and high-risk patients. A HRQOL assessment was performed at five time points (immediately before the initiation of C-ion RT, immediately after, and at 12, 36 and 60 months after completion of C-ion RT) using Functional Assessment of Cancer Therapy (FACT) questionnaires. FACT-G and FACT-P scores were significantly decreased; however, the absolute change after 60 months was minimal. The transient decreases in the Trial Outcome Index (TOI) score returned to their baseline levels. Use of ADT, presence of adverse events, and biochemical failure were related to lower scores. Scores of subdomains of FACT instruments indicated characteristic changes. The pattern of HRQOL change after C-ion RT was similar to that of other modalities. Further controlled studies focusing on a HRQOL in patients with prostate cancer are warranted.学位の種類: 博士（医学）. 報告番号: 甲第4242号. 学位記番号: 新大院博（医）甲第720号. 学位授与年月日: 平成29年3月23日The Journal of Radiation Research 58(2)260-266,2017新大院博（医）甲第720号
- DOI
- info:doi/10.1093/jrr/rrw122
- Persistent ID (NDL)
- info:ndljp/pid/10371254
- Collection
- Collection (Materials For Handicapped People:1)
- Collection (particular)
- 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
- Acquisition Basis
- 博士論文（自動収集）
- Date Accepted (W3CDTF)
- 2017-07-03T04:10:06+09:00
- Date Created (W3CDTF)
- 2019-08-05
- Format (IMT)
- application/pdf
- Access Restrictions
- 国立国会図書館内限定公開
- Service for the Digitized Contents Transmission Service
- 図書館・個人送信対象外
- Availability of remote photoduplication service
- 可
- Periodical Title (URI)
- Data Provider (Database)
- 国立国会図書館 : 国立国会図書館デジタルコレクション