Survey on the management of physical risks induced by psychotropic agents in Japan

• 資料種別: 博士論文
• タイトル: Survey on the management of physical risks induced by psychotropic agents in Japan
• 著者・編者: Orime, Naoki
• 出版事項: 新潟大学
• 出版年月日等: 2018-03-23
• 出版年（W3CDTF）: 2018-03-23
• 並列タイトル等: Survey on the management of physical risks induced by psychotropic agents in Japan; 日本における向精神薬による身体リスク管理の調査研究
• 授与機関名: 新潟大学
• 授与年月日: 2018-03-23
• 授与年月日（W3CDTF）: 2018-03-23
• 報告番号: 甲第4410号
• 学位: 博士（医学）
• 博論授与番号: 甲第4410号
• 本文の言語コード: eng
• 件名標目: monitoring; pharmacotherapy; psychotropic agents; retrospective study; side-effect
• 一般注記: Purpose: Several treatment guidelines recommend periodic monitoring (i.e., once per year) of side-effects in patients taking psychotropic agents. However, the actual frequency of side-effects monitoring is unclear. Accordingly, we investigated the frequency of side-effects monitoring in Japanese patients. Methods: We used the national insurance claim database to identify patients prescribed with psychotropic agents for more than 3 years. Among these patients, we identified those who had undergone electrocardiogram, liver or kidney function, serum lipid level, blood glucose level, and serum prolactin level assessment at least once per year for 3 years of treatment. We classified these patients into adults and children and compared the frequency of each examination between the two groups. Results: A total of 8822 patients were included in the analysis. The frequencies of electrocardiogram, blood glucose level, serum lipid level, liver or kidney function, and serum prolactin level monitoring were <0.1%, 16.4%, 16.5%, 20.6%, and 1.1%, respectively. In patients taking antipsychotic agents, children were significantly less frequently screened for blood glucose level, serum lipid level, and liver or kidney function compared with adults (p < 0.01). Conclusion: Our data suggest that the frequency of side-effects monitoring in persistent users of psychotropic agents in Japan was lower than that recommended by several guidelines.; 学位の種類: 博士（医学）. 報告番号: 甲第4410号. 学位記番号: 新大院博（医）甲第809号. 学位授与年月日: 平成30年3月23日; Clinical Neuropsychopharmacology and Therapeutics. 2017. 8, 42-46.; 新大院博（医）甲第809号
• DOI: info:doi/10.5234/cnpt.8.42; https://doi.org/info:doi/10.5234/cnpt.8.42
• 国立国会図書館永続的識別子: info:ndljp/pid/11123984; https://dl.ndl.go.jp/pid/11123984
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2018-08-03T23:36:01+09:00
• 作成日（W3CDTF）: 2019-08-05
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10191/50432
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp