Survey on the management of physical risks induced by psychotropic agents in Japan

• Material Type: 博士論文
• Title: Survey on the management of physical risks induced by psychotropic agents in Japan
• Author/Editor: Orime, Naoki
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2018-03-23
• Publication Date (W3CDTF): 2018-03-23
• Alternative Title: Survey on the management of physical risks induced by psychotropic agents in Japan; 日本における向精神薬による身体リスク管理の調査研究
• Degree grantor/type: 新潟大学
• Date Granted: 2018-03-23
• Date Granted (W3CDTF): 2018-03-23
• Dissertation Number: 甲第4410号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第4410号
• Text Language Code: eng
• Subject Heading: monitoring; pharmacotherapy; psychotropic agents; retrospective study; side-effect
• Note (General): Purpose: Several treatment guidelines recommend periodic monitoring (i.e., once per year) of side-effects in patients taking psychotropic agents. However, the actual frequency of side-effects monitoring is unclear. Accordingly, we investigated the frequency of side-effects monitoring in Japanese patients. Methods: We used the national insurance claim database to identify patients prescribed with psychotropic agents for more than 3 years. Among these patients, we identified those who had undergone electrocardiogram, liver or kidney function, serum lipid level, blood glucose level, and serum prolactin level assessment at least once per year for 3 years of treatment. We classified these patients into adults and children and compared the frequency of each examination between the two groups. Results: A total of 8822 patients were included in the analysis. The frequencies of electrocardiogram, blood glucose level, serum lipid level, liver or kidney function, and serum prolactin level monitoring were <0.1%, 16.4%, 16.5%, 20.6%, and 1.1%, respectively. In patients taking antipsychotic agents, children were significantly less frequently screened for blood glucose level, serum lipid level, and liver or kidney function compared with adults (p < 0.01). Conclusion: Our data suggest that the frequency of side-effects monitoring in persistent users of psychotropic agents in Japan was lower than that recommended by several guidelines.; 学位の種類: 博士（医学）. 報告番号: 甲第4410号. 学位記番号: 新大院博（医）甲第809号. 学位授与年月日: 平成30年3月23日; Clinical Neuropsychopharmacology and Therapeutics. 2017. 8, 42-46.; 新大院博（医）甲第809号
• DOI: info:doi/10.5234/cnpt.8.42; https://doi.org/info:doi/10.5234/cnpt.8.42
• Persistent ID (NDL): info:ndljp/pid/11123984; https://dl.ndl.go.jp/pid/11123984
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2018-08-03T23:36:01+09:00
• Date Created (W3CDTF): 2019-08-05
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10191/50432
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp