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博士論文

Survey on the management of physical risks induced by psychotropic agents in Japan

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Survey on the management of physical risks induced by psychotropic agents in Japan

Persistent ID (NDL)
info:ndljp/pid/11123984
Material type
博士論文
Author
Orime, Naoki
Publisher
新潟大学
Date granted
2018-03-23
Material Format
Digital
Capacity, size, etc.
-
Degree grantor and degree
新潟大学,博士(医学)
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Note (General):

Purpose: Several treatment guidelines recommend periodic monitoring (i.e., once per year) of side-effects in patients taking psychotropic agents. Howe...

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Digital

Material Type
博士論文
Author/Editor
Orime, Naoki
Publication, Distribution, etc.
Publication Date
2018-03-23
Publication Date (W3CDTF)
2018-03-23
Alternative Title
Survey on the management of physical risks induced by psychotropic agents in Japan
日本における向精神薬による身体リスク管理の調査研究
Degree Grantor
新潟大学
Date Granted
2018-03-23
Date Granted (W3CDTF)
2018-03-23
Dissertation Number
甲第4410号
Degree Type
博士(医学)
Conferring No. (Dissertation)
甲第4410号
Text Language Code
eng
Note (General)
Purpose: Several treatment guidelines recommend periodic monitoring (i.e., once per year) of side-effects in patients taking psychotropic agents. However, the actual frequency of side-effects monitoring is unclear. Accordingly, we investigated the frequency of side-effects monitoring in Japanese patients. Methods: We used the national insurance claim database to identify patients prescribed with psychotropic agents for more than 3 years. Among these patients, we identified those who had undergone electrocardiogram, liver or kidney function, serum lipid level, blood glucose level, and serum prolactin level assessment at least once per year for 3 years of treatment. We classified these patients into adults and children and compared the frequency of each examination between the two groups. Results: A total of 8822 patients were included in the analysis. The frequencies of electrocardiogram, blood glucose level, serum lipid level, liver or kidney function, and serum prolactin level monitoring were <0.1%, 16.4%, 16.5%, 20.6%, and 1.1%, respectively. In patients taking antipsychotic agents, children were significantly less frequently screened for blood glucose level, serum lipid level, and liver or kidney function compared with adults (p < 0.01). Conclusion: Our data suggest that the frequency of side-effects monitoring in persistent users of psychotropic agents in Japan was lower than that recommended by several guidelines.
学位の種類: 博士(医学). 報告番号: 甲第4410号. 学位記番号: 新大院博(医)甲第809号. 学位授与年月日: 平成30年3月23日
Clinical Neuropsychopharmacology and Therapeutics. 2017. 8, 42-46.
新大院博(医)甲第809号
Persistent ID (NDL)
info:ndljp/pid/11123984
Collection (Materials For Handicapped People:1)
Collection (particular)
国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
Acquisition Basis
博士論文(自動収集)
Date Accepted (W3CDTF)
2018-08-03T23:36:01+09:00
Date Created (W3CDTF)
2019-08-05
Format (IMT)
application/pdf
Access Restrictions
国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service
図書館・個人送信対象外
Availability of remote photoduplication service
Data Provider (Database)
国立国会図書館 : 国立国会図書館デジタルコレクション