Effects of sugar-sweetened beverage intake on the development of type 2 diabetes mellitus in subjects with impaired glucose tolerance: the Mihama Diabetes Prevention Study

• 資料種別: 博士論文
• タイトル: Effects of sugar-sweetened beverage intake on the development of type 2 diabetes mellitus in subjects with impaired glucose tolerance: the Mihama Diabetes Prevention Study
• 著者・編者: TESHIMA, Nobuko
• 著者標目: TESHIMA, Nobuko
• 出版事項: 三重大学
• 出版年月日等: 2015-07-15
• 出版年（W3CDTF）: 2015-07-15
• 授与機関名: 三重大学
• 授与年月日: 2015-07-15
• 授与年月日（W3CDTF）: 2015-07-15
• 報告番号: 乙医学第984号
• 学位: 博士(医学)
• 博論授与番号: 乙医学第984号
• 本文の言語コード: eng
• 著者別名: テシマ, ノブコ; 手島, 信子
• 件名標目: type 2 diabetes; sugar intake; sweetened beverage; nutritional behavior; cohort study
• 対象利用者: 一般
• 一般注記: application/pdf; In Japan, the incidence of type 2 diabetes mellitus (T2DM) is increasing for several reasons, including increased consumption of sugar-sweetened beverages (SSBs). However, whether SSBs cause T2DM by excess of energy production resulting in obesity remains unclear. Therefore, the present study was designed to evaluate the effects of SSB intake on the development of T2DM in subjects with impaired glucose tolerance (IGT). Ninety-three subjects (30 males and 63 females) with IGT aged 40-69 y and residing in the Mihama district (southern Mie Prefecture, Japan) were included in the study. The mean observational period was 3.6 y. All subjects underwent the 75-g oral glucose tolerance test (OGTT)and completed a lifestyle questionnaire survey related to SSB intake. OGTT results and SSB intake were evaluated before and after the observational period. In addition, the correlation between SSB intake and development of T2DM was investigated. Of the 93 subjects, 20(21.5%) developed T2DM (T2DM group) and demonstrated a significantly high SSB intake compared with the group that did not develop the disease (non-T2DM group). The odds ratio for the incidence of T2DM based on SSB intake was 3.26 (95% confidence interval, 1.17-90.6). The body mass index (BMI; kg/m2) and the homeostasis model assessment for insulin resistance (HOMA-R) values was significantly higher in the T2DM group than in the non-T2DM group, while the insulinogenic indices were significantly lower in the former than in the latter group. The sum of insulin secretion levels during OGTT was not significantly different between groups. SSB intake correlated with the predisposition for developing T2DM, possibly by influencing body weight, insulin resistance, and the ability of the pancreatic beta cells to effectively compensate for the insulin resistance.; 本文/Division of Dietary Service.Mie University Hospital; 6p
• DOI: info:doi/10.3177/jnsv.61.14; https://doi.org/info:doi/10.3177/jnsv.61.14
• 国立国会図書館永続的識別子: info:ndljp/pid/11526697; https://dl.ndl.go.jp/pid/11526697
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2020-08-11T22:41:34+09:00
• 作成日（W3CDTF）: 2020-07-29
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10076/00019136; https://mie-u.repo.nii.ac.jp/records/13518
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

目次

2023-12-15 再収集